Title
Non-coding RNAs and cancer [electronic resource] / Muller Fabbri, editor.
ISBN
9781461484448 electronic book
1461484448 electronic book
9781461484431
Published
New York, NY : Springer, 2014.
Language
English
Description
1 online resource (vi, 284 pages) : color illustrations
Item Number
10.1007/978-1-4614-8444-8 doi
Call Number
QP623
Dewey Decimal Classification
572.8/8
Summary
The discovery of microRNAs and its role as gene expression regulators in human carcinogenesis represents one of the most important scientific achievements of the last decade. More recently, other non-coding RNAs have been discovered and?its implications in cancer are emerging as well, suggesting a broader than anticipated involvement of the non-coding genome in cancer. Moreover, completely new and unexpected functions for microRNAs are being revealed, leading to the identification of new anticancer molecular targets. This book represents a comprehensive guide on non-coding RNAs and cancer, spanning from its role as cancer biomarkers, to providing the most useful bioinformatic tools, to presenting some of the most relevant discoveries, which indicates how these fascinating molecules act as fine orchestrators of cancer biology.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Description based on online resource; title from PDF title page (SpringerLink, viewed November 4, 2013).
Biogenesis and Physiology of microRNAs.-Detecting non-coding RNA expression: from arrays to next generation sequencing
MicroRNAs in Solid Tumors.-MicroRNAs in hematologic malignancies
miRNAs as Cancer Biomarkers
Unraveling the complex network of interactions between non-coding RNAs and epigenetics in cancer
MicroRNA SNPs in Cancer
Bioinformatics Approaches to the study of microRNAs
Beyond miRNAs: role of other non-coding RNAs in cancer
Translational Implications for non-coding RNA in Cancer.
