@article{695956,
      recid = {695956},
      author = {Jones, Lynne C., and Haggard, Warren O., and Greenwald, A.  Seth,},
      title = {Metal-on-metal bearings a clinical practicum / [electronic  resource] :},
      pages = {1 online resource (x, 200 pages) :},
      abstract = {This book addresses the background and significance of the  factors potentially influencing the clinical and biological  outcomes of metal-on-metal hip implants. Metal-on-metal  bearings were introduced and evaluated as an alternative to  other bearing couples, particularly metal-on-polyethylene,  due to their enhanced wear resistance as determined in  laboratory testing. Initially, reports of short-term  clinical outcomes were favorable and an increasing number  of metal-on-metal prostheses were implanted. Subsequently,  isolated case findings describing adverse tissue responses  around the articulation became the harbinger of an  increasing number of reports describing pseudotumors and  other significant lymphocytic-based responses associated  with metal-on-metal prostheses. Questions have been raised  as to whether this is an implant, design, or  patient-specific response. The reasons why some patients  have a negative biological response and pathology while  others do not remain to be determined, but tens of  thousands of patients in the US, the UK, and around the  world are considered to be at risk. Leading researchers and  clinicians describe the issues related to the nature of the  biological and pathological responses and the protocols  that should be followed to determine if an adverse response  is occurring.},
      url = {http://library.usi.edu/record/695956},
      doi = {https://doi.org/10.1007/978-1-4614-8999-3},
}