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Bone metastases [electronic resource] : a translational and clinical approach / Dimitrios Kardamakis, Vassilios Vassiliou, Edward Chow, editors.

Kardamakis, Dimitrios, editor of compilation.; Vassiliou, Vassilios, editor of compilation.; Chow, Edward, editor of compilation.
2014
RC280.B6
Available Online
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Title
Bone metastases [electronic resource] : a translational and clinical approach / Dimitrios Kardamakis, Vassilios Vassiliou, Edward Chow, editors.
Edition
Second edition.
ISBN
9789400775695 electronic book
9400775695 electronic book
9789400775688
DOI
https://doi.org/10.1007/978-94-007-7569-5
Published
Dordrecht : Springer, 2014.
Language
English
Description
1 online resource (ix, 490 pages) : illustrations.
Item Number
10.1007/978-94-007-7569-5 doi
Call Number
RC280.B6
Dewey Decimal Classification
616.99471
Summary
The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Source of Description
Description based on print version record.
Added Author
Kardamakis, Dimitrios, editor of compilation.
Vassiliou, Vassilios, editor of compilation.
Chow, Edward, editor of compilation.
Series
Cancer metastasis ; v.21.
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Preface. I Fundamental Concepts
Pathophysiology of metastatic bone disease
Bone metastases: epidemiology, clinical picture, SREs and prognosis
Pain in bone metastases: types and mechanisms. II Investigations Of Bone Metastases
Radiological evaluations: radiography, CT, MRI.-Nuclear medicine imaging modalities: bone scintigraphy, PET-CT, SPECT.-Bone turnover markers
New omics approaches for bone metastases. III Therapeutic Management.-Analgesic treatment for bone mets
Radiotherapy: external beam and radio-surgery
Radionuclide therapy
Bisphosphonates
New targeted therapies for bone metastases
Chemotherapy and hormone therapy
HIFU/Radioablation
Neuropathic bone metastases
Spinal cord compression and cauda equina compression
Pathological and impending fracture
Re-irradiation
Bone metastases in elderly patients
Management of metastatic bone disease in the elderly with bisphosphonates and RANKL inhibitors: effectiveness and safety. IV Assesment of Therapeutic Response
Radiological and nuclear medicine imaging modalities.-Clinical assessment measures
Outcome measures in bone metastases clinical trials
Quality of life in patients suffering from metastatic skeletal disease. V Cost of Managing Metastatic Bone Disease
Cost effectiveness of treatment modalities for bone metastases
Index.

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