000696068 000__ 04124cam\a2200481Ii\4500 000696068 001__ 696068 000696068 005__ 20230306135514.0 000696068 006__ m\\\\\o\\d\\\\\\\\ 000696068 007__ cr\cnu|||unuuu 000696068 008__ 131217s2014\\\\nyua\\\\o\\\\\001\0\eng\d 000696068 020__ $$a9781461482475 $$qelectronic book 000696068 020__ $$a146148247X $$qelectronic book 000696068 020__ $$z9781461482468 000696068 0247_ $$a10.1007/978-1-4614-8247-5$$2doi 000696068 035__ $$aSP(OCoLC)ocn865504957 000696068 035__ $$aSP(OCoLC)865504957 000696068 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dN$T$$dYDXCP$$dCOO$$dOCLCA$$dOHS 000696068 049__ $$aISEA 000696068 050_4 $$aRM301.25 000696068 08204 $$a615.1/9$$223 000696068 24500 $$aPharmaco-imaging in drug and biologics development$$h[electronic resource] :$$bfundamentals and applications /$$cBrian R. Moyer, Narayan P.S. Cheruvu, Tom C.-C. Hu, editors. 000696068 264_1 $$aNew York, NY :$$bSpringer,$$c2014. 000696068 300__ $$a1 online resource (xvii, 401 pages) :$$billustrations (some color). 000696068 336__ $$atext$$btxt$$2rdacontent 000696068 337__ $$acomputer$$bc$$2rdamedia 000696068 338__ $$aonline resource$$bcr$$2rdacarrier 000696068 4901_ $$aAAPS Advances in the Pharmaceutical Sciences Series,$$x2210-7371 ;$$v8 000696068 500__ $$aIncludes index. 000696068 5050_ $$aImaging Platforms and Drug Development: An Introduction -- Imaging in Drug Development: Animal Models, Handling and Physiological Constraints -- Considerations for Pre-Clinical Laboratory Animal Imaging Center Design, Setup, and Management suitable for Biomedical Investigation for Drug Discovery -- Pharmaco-Imaging in Translational Science and Research -- The Role of Pharmacokinetics and Allometrics in Imaging: Practical Issues and Considerations -- Quantitative Imaging Using Autoradiographic Techniques -- Pre-Clinical Imaging in Oncology: Considerations and Recommendations for the Imaging Scientist -- Use of Radiolabelled Leukocytes for Drug Evaluation in Man -- Application of Bioluminescence Imaging (BLI) to the Study of the Animal Models of Human Infectious Diseases -- Pre-Clinical Imaging in BSL-3 and BSL-4 Environments: Imaging Pathophysiology of Highly Pathogenic Infectious Diseases -- Magnetic Resonance as a Tool for Pharmaco-Imaging -- Technologies and Principles of Mass Spectral Imaging -- Regulatory Considerations Involved In Imaging. 000696068 506__ $$aAccess limited to authorized users. 000696068 520__ $$aAdvances in drugs and biologics to mitigate or cure some of nature's most complex medical problems have been incredible to behold. These accomplishments are due to the actions of a wide theatre of participants from biologists, pharmacologists, geneticists, chemists and manufacturers, molecular biologists, toxicologists, clinicians, nurses, program managers, quality assurance personnel, regulatory professionals and a new group of innovators the Imaging Scientists. Imaging has grown from the microscopy sections put on slides with special stains to now in vivo slices created with innovative physics, imaging tracers and contrast agents, and incredibly fast and accurate computational systems. The world of biology has become one of witnessing the actions of drugs and biologics through the window of mechanical and electrical engineering creating instruments and reporter molecules that can help us see into our bodies and paint them with medical information needed to resolve disease. This book will inspire imagination and elicit even more innovations in the development of new and novel drugs and biologics through imaging. 000696068 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed November 11, 2013). 000696068 650_0 $$aDrug development. 000696068 650_0 $$aDrugs$$xAnalysis. 000696068 650_0 $$aPharmaceutical industry$$xTechnological innovations. 000696068 7001_ $$aMoyer, Brian R.,$$eeditor of compilation. 000696068 7001_ $$aCheruvu, Narayan P. S.,$$eeditor of compilation. 000696068 7001_ $$aHu, Tom C.-C.,$$eeditor of compilation. 000696068 830_0 $$aAAPS advances in the pharmaceutical sciences series ;$$v8.$$x2210-7371 000696068 85280 $$bebk$$hSpringerLink 000696068 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4614-8247-5$$zOnline Access 000696068 909CO $$ooai:library.usi.edu:696068$$pGLOBAL_SET 000696068 980__ $$aEBOOK 000696068 980__ $$aBIB 000696068 982__ $$aEbook 000696068 983__ $$aOnline 000696068 994__ $$a92$$bISE