[Beta]-barrel channel proteins as tools in nanotechnology [electronic resource] : biology, basic science and advanced applications / Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero.
Fioroni, Marco, author.; Dworeck, Tamara, author.; Rodriguez-Ropero, Francisco, author.
2014
QP552.M44
Available Online

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Title [Beta]-barrel channel proteins as tools in nanotechnology [electronic resource] : biology, basic science and advanced applications / Marco Fioroni, Tamara Dworeck, Francisco Rodriguez-Ropero.
Author Fioroni, Marco, author.
ISBN 9789400774292 electronic book
940077429X electronic book
9789400774285
DOI https://doi.org/10.1007/978-94-007-7429-2
Published Dordrecht : Springer, 2014.
Language English
Description 1 online resource (xii, 168 pages) : illustrations.
Item Number 10.1007/978-94-007-7429-2 doi
Call Number QP552.M44
Dewey Decimal Classification 572/.696
Summary b-barrel outer membrane channel proteins (OMP) have great potential as robust and flexible models or components in nanotechnology. Over the last decade biotechnological techniques allowed to expand the natural characteristics of OMPs by modifying their geometry and properties without affecting the overall protein structure and stability. The present book is oriented towards a broad group of readers including graduate students and advanced researchers. The b-barrel structure serviceability for the nano-material design will be its chief topic giving a general introduction to the field of OMP based nano-component development as well as the state of the art of the involved research. On the example of the E. coli FhuA the transformation of an OMP into a tailored nano-channel to be adapted to a non-biological synthetic (i.e. polymer) environment, rendering it competitive with artificial non-biological nano-pores will be outlined specifically the design of a set of protein nano-channels with tailored geometry (diameter, length), conductance and functionality will be reported as a case study. In order to make this book a valuable source of information for both biotechnologists and other scientists interested in bio-nanotechnology an overview of the different steps involved in the nano-channel protein design and production will be reported. The scientific strategy from concept design, theoretical considerations, genetic engineering and large scale production, to system assembly and biophysical characterization with an overview on technological applications including membrane/polymersome technology, will be described.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Description based on online resource; title from PDF title page (SpringerLink, viewed November 11, 2013).
Added Author Dworeck, Tamara, author.
Rodriguez-Ropero, Francisco, author.
Series Advances in experimental medicine and biology ; v.794.
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Record Appears in Online Resources > Ebooks
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Biology
Biophysical Characterization
Theoretical Considerations and Computational Tools
Biotechnology
Technological Applications
Final Considerations.

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