000696094 000__ 04641cam\a2200433Ii\4500 000696094 001__ 696094 000696094 005__ 20230306135515.0 000696094 006__ m\\\\\o\\d\\\\\\\\ 000696094 007__ cr\cnu|||unuuu 000696094 008__ 131218s2014\\\\nyua\\\\o\\\\\000\0\eng\d 000696094 020__ $$a9781461486909 $$qelectronic book 000696094 020__ $$a1461486904 $$qelectronic book 000696094 020__ $$z9781461486893 000696094 0247_ $$a10.1007/978-1-4614-8690-9$$2doi 000696094 035__ $$aSP(OCoLC)ocn865546772 000696094 035__ $$aSP(OCoLC)865546772 000696094 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dN$T$$dYDXCP$$dCOO$$dOHS 000696094 049__ $$aISEA 000696094 050_4 $$aRD593 000696094 08204 $$a617.4/8$$223 000696094 24500 $$aVascular mechanisms in CNS trauma$$h[electronic resource] /$$cEng H. Lo, Josephine Lok, MingMing Ning, Michael J. Whalen, editors. 000696094 264_1 $$aNew York, NY :$$bSpringer,$$c2014. 000696094 300__ $$a1 online resource (xx, 518 pages) :$$billustrations (some color) 000696094 336__ $$atext$$btxt$$2rdacontent 000696094 337__ $$acomputer$$bc$$2rdamedia 000696094 338__ $$aonline resource$$bcr$$2rdacarrier 000696094 4901_ $$aSpringer Series in Translational Stroke Research 000696094 5050_ $$aCNS Barriers in Neurotrauma -- Mechanisms of Cerebral Edema Leading to Early Seizures after Traumatic Brain Injury -- Human Cerebral Blood Flow and Traumatic Brain Injury -- Gliovascular Targets in Traumatic CNS Injury -- Neurovascular Responses to Traumatic Brain Injury -- The Effects of Intravascular Coagulation and Microthrombosis on Cerebral Perfusion after Brain Trauma -- Barriers to Drug Delivery for Brain Trauma -- Angiogenesis and Functional Recovery after Traumatic Brain Injury -- Vascular Mechanisms in Spinal Cord Injury -- Neurovascular Mechanisms of Ischemia Tolerance Against Brain Injury -- Stem Cells for Neurovascular Repair in CNS Trauma -- Vascular Actions of Hypothermia in Brain Trauma -- Vascular Responses in Rodent Models of Traumatic Brain Injury -- SAH Models: Review, New Modification, and Prospective -- Age and Sex Differences In Hemodynamics In a Large Animal Model of Brain Trauma -- Neutrophils as Determinants of Vascular Stability in the Injured Spinal Cord -- Blood Biomarkers for Acute CNS Insults: Traumatic Brain Injury and Stroke -- Biomaterials for CNS Injury -- Isolated Blood Vessel Models for Studying Trauma -- Managing Edema and Intracranial Pressure in the Intensive Care Unit -- Surgical Management of Traumatic Brain Edema -- Optimizing Hemodynamics in the Clinical Setting -- Cerebrovascular Autoregulation and Monitoring of Cerebrovascular Reactivity -- Cerebrovascular Responses after Pediatric Traumatic Brain Injury -- Subdural Hematoma in Non-Accidental Head Injury -- Blood Genomics after Brain Ischemia, Hemorrhage, and Trauma -- Molecular Biomarkers in Neurocritical Care ? The Next Frontier -- Bedside Monitoring of Vascular Mechanisms in CNS Trauma: The use of Near Infra-red Spectroscopy (NIRS) and Transcranial Doppler (TCD) -- In vivo MRI and MRS of Cerebrovascular Function following Traumatic Brain Injury. 000696094 506__ $$aAccess limited to authorized users. 000696094 520__ $$aVascular Mechanisms in CNS Trauma focuses on the vascular aspects of brain and spinal cord trauma.Twenty nine chapters are arranged in three sections:Molecular Mechanisms; Experimental Models and Methods; and Clinical Challenges and Opportunities. The first section addresses topics in the basic biology of brain and spinal cord trauma, ranging from the pathophysiology of cerebral endothelial cells and gliovascular interactions to the role of stem cells in neurovascular repair. The second section covers experimental methods in rodent and in large animal models of CNS injury, as well as the use of biomaterials and biomarkers in studying the mechanisms of tissue response. The third section deals with clinical issues in the monitoring and treatment of the patient with traumatic injury of the brain and spinal cord. Contributors to the book include an integrated mix of basic scientists and clinicians from diverse institutions. By presenting salient issues in CNS trauma from a vascular perspective, this book should make a unique contribution to the understanding of traumatic brain and spinal cord injury. 000696094 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed November 11, 2013). 000696094 650_0 $$aCentral nervous system$$xWounds and injuries. 000696094 650_0 $$aCerebrovascular diseases. 000696094 7001_ $$aLo, Eng H.,$$eeditor of compilation. 000696094 830_0 $$aSpringer series in translational stroke research. 000696094 85280 $$bebk$$hSpringerLink 000696094 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4614-8690-9$$zOnline Access 000696094 909CO $$ooai:library.usi.edu:696094$$pGLOBAL_SET 000696094 980__ $$aEBOOK 000696094 980__ $$aBIB 000696094 982__ $$aEbook 000696094 983__ $$aOnline 000696094 994__ $$a92$$bISE