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Thymic development and selection of T Lymphocytes [electronic resource] / Thomas Boehm, Yousuke Takahama, editors.

Boehm, T. L. J. (Thomas L. J.), 1956-, editor of compilation.; Takahama, Yousuke, editor of compilation.
2014
QR185.8.T2
Available Online
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Title
Thymic development and selection of T Lymphocytes [electronic resource] / Thomas Boehm, Yousuke Takahama, editors.
ISBN
9783642402524 electronic book
3642402526 electronic book
9783642402517
DOI
https://doi.org/10.1007/978-3-642-40252-4
Published
Heidelberg : Springer, 2014.
Language
English
Description
1 online resource (vii, 132 pages) : illustrations (some color).
Item Number
10.1007/978-3-642-40252-4 doi
Call Number
QR185.8.T2
Dewey Decimal Classification
571.9/66
Summary
The thymus is an evolutionarily ancient primary lymphoid organ common to all vertebrates in which T cell development takes place. Failing thymus function is associated with immunodeficiency and/or autoimmunity. In this volume, leading experts provide a comprehensive overview of recent advances in thymopoiesis research. The chapters cover the development of the thymic epithelial microenvironment, address the formation of a diverse and self-tolerant repertoire of T cell receptors as the basis for cellular immunity, discuss the mechanisms by which progenitor cells colonize the thymus and detail the molecular basis for T lineage decisions. The reviews illustrate the important role of the multifaceted process of thymopoiesis for adaptive immunity.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Description based on online resource; title from PDF title page (SpringerLink, viewed November 11, 2013).
Added Author
Boehm, T. L. J. (Thomas L. J.), 1956-, editor of compilation.
Takahama, Yousuke, editor of compilation.
Series
Current topics in microbiology and immunology ; v.373. 0070-217X
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All Resources
Development and Function of Cortical Thymic Epithelial Cells
Mechanisms of Thymus Medulla Development And Function
Self-peptides in TCR Repertoire Selection and Peripheral T Cell Function
Central Tolerance Induction
Trafficking to the Thymus
The CD4/CD8 Lineages: Central Decisions and Peripheral Modifications for T Lymphocytes.

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