000696113 000__ 03810cam\a2200445Ii\4500 000696113 001__ 696113 000696113 005__ 20230306135516.0 000696113 006__ m\\\\\o\\d\\\\\\\\ 000696113 007__ cr\cnu|||unuuu 000696113 008__ 131219s2014\\\\nyua\\\\o\\\\\001\0\eng\d 000696113 020__ $$a9781461489153 $$qelectronic book 000696113 020__ $$a1461489156 $$qelectronic book 000696113 020__ $$z9781461489146 000696113 0247_ $$a10.1007/978-1-4614-8915-3$$2doi 000696113 035__ $$aSP(OCoLC)ocn865576166 000696113 035__ $$aSP(OCoLC)865576166 000696113 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dN$T$$dIDEBK$$dYDXCP$$dCOO$$dOHS 000696113 049__ $$aISEA 000696113 050_4 $$aRD594 000696113 08204 $$a617.4/81044$$223 000696113 24500 $$aImmunological mechanisms and therapies in brain injuries and stroke$$h[electronic resource] /$$cJun Chen, Xiaoming Hu, Mary Stenzel-Poore, John H. Zhang, editors. 000696113 264_1 $$aNew York, NY :$$bSpringer,$$c2014. 000696113 300__ $$a1 online resource (x, 386 pages) :$$billustrations (some color). 000696113 336__ $$atext$$btxt$$2rdacontent 000696113 337__ $$acomputer$$bc$$2rdamedia 000696113 338__ $$aonline resource$$bcr$$2rdacarrier 000696113 4901_ $$aSpringer Series in Translational Stroke Research 000696113 500__ $$aIncludes index. 000696113 5050_ $$aOld dogmas, surprising complexities, and novel therapeutic targets -- The critical roles of immune cells in acute brain injuries -- Vascular Inflammation in Ischemic Stroke: Adhesion Receptors Controlling Leukocyte-Endothelial Interactions -- Immune Cell-Derived Free Radicals in Acute Brain Injury -- The complement cascade in acute brain injury -- Matrix Metalloproteinases as an Inflammatory Mediator in the Neurovascular Unit -- Toll-Like Receptors in Ischemic Stroke and other Acute Brain Injuries -- Ion Transporters in Microglial Function: New therapeutic targets for neuroinflammation in ischemic stroke? -- Inflammation After Acute Brain Injuries Affects the Developing Brain Differently than the Adult Brain -- Systemic Immune Responses after Experimental Stroke -- Infectious Burden and Risk of Stroke -- Inflammatory Biomarkers in Patients with Acute Brain Injuries -- In vivo Imaging of Neuroinflammation in Acute Brain Injury -- Inflammation as a therapeutic target after subarachnoid hemorrhage: advances and challenges -- Minocycline, a Tetracycline Derivative, as a Potential Protective Agent for Acute Stroke -- Tolerization to Brain and Vascular Antigens: Targeting Autoimmunity after Acute Brain Injuries and Preventing Stroke -- The Role of PPARg in Stroke -- CD36: an inflammatory mediator in acute brain injury -- Cool Down the Inflammation: Hypothermia as a Therapeutic Strategy for Acute Brain Injuries. 000696113 506__ $$aAccess limited to authorized users. 000696113 520__ $$aRecent research has revealed the importance of immunological mechanisms and inflammation in delaying damage and/or promoting repair after an acute injury to the central nervous system. This book provides a comprehensive and up-to-date overview of the role of immunological mechanisms and therapies for treating acute neurological injuries such as cerebral ischemia, hemorrhage, and brain and spinal cord trauma. In several sections, the contributing authors provide a review of immunological mechanisms involved in neurological injury and of various translational and clinical research aimed at harnessing those mechanisms for better patient outcomes. 000696113 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed November 11, 2013). 000696113 650_0 $$aBrain$$xWounds and injuries$$xTreatment. 000696113 650_0 $$aCerebrovascular disease$$xTreatment. 000696113 7001_ $$aChen, Jun,$$eeditor of compilation. 000696113 830_0 $$aSpringer series in translational stroke research. 000696113 85280 $$bebk$$hSpringerLink 000696113 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4614-8915-3$$zOnline Access 000696113 909CO $$ooai:library.usi.edu:696113$$pGLOBAL_SET 000696113 980__ $$aEBOOK 000696113 980__ $$aBIB 000696113 982__ $$aEbook 000696113 983__ $$aOnline 000696113 994__ $$a92$$bISE