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000696304 020__ $$a9780387756134 $$qelectronic book
000696304 020__ $$a0387756132 $$qelectronic book
000696304 020__ $$z9780387756127
000696304 0247_ $$a10.1007/978-0-387-75613-4$$2doi
000696304 035__ $$aSP(OCoLC)ocn864443756
000696304 035__ $$aSP(OCoLC)864443756
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000696304 050_4 $$aRM267
000696304 08204 $$a615.7922$$222
000696304 24500 $$aFundamentals of antimicrobial pharmacokinetics and pharmacodynamics$$h[electronic resource]  /$$cedited by Alexander Vinks, Hartmut Derendorf, Johan Mouton.
000696304 264_1 $$aNew York :$$bSpringer,$$c2014.
000696304 300__ $$a1 online resource.
000696304 336__ $$atext$$btxt$$2rdacontent
000696304 337__ $$acomputer$$bc$$2rdamedia
000696304 338__ $$aonline resource$$bcr$$2rdacarrier
000696304 500__ $$aIncludes index.
000696304 5050_ $$aForeword -- Section I: Basic Concepts and Principles -- Introduction to Pharmacodynamics and micrbiology -- In vitro and animal PK/PD model -- MIC and breakpoints -- Principles of applied PK/PD modeling -- Population Pk/PD modeling and its applications to antimicrobials -- Drug resistance and Drug-drug combinations -- Section II: Clinical -- Aminoglycosides -- Beta-lactam antibiotics including continuous infusion -- Macrolides -- Glycopeptides -- Quinolones -- Other.-.$$cỹ
000696304 506__ $$aAccess limited to authorized users.
000696304 520__ $$aOver the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics is designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader is introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, from basic research to clinical situations.
000696304 588__ $$aDescription based on print version record.
000696304 650_0 $$aAnti-infective agents$$xPharmacokinetics.
000696304 650_0 $$aAnti-infective agents$$xDose-response relationship.
000696304 7001_ $$aVinks, Alexander,$$eeditor of compilation.
000696304 7001_ $$aDerendorf, Hartmut,$$eeditor of compilation.
000696304 7001_ $$aMouton, Johan,$$eeditor of compilation.
000696304 77608 $$iPrint version:$$tFundamentals of antimicrobial pharmacokinetics and pharmacodynamics$$z9780387756127$$w(OCoLC)567208272
000696304 85280 $$bebk$$hSpringerLink
000696304 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-0-387-75613-4$$zOnline Access
000696304 909CO $$ooai:library.usi.edu:696304$$pGLOBAL_SET
000696304 980__ $$aEBOOK
000696304 980__ $$aBIB
000696304 982__ $$aEbook
000696304 983__ $$aOnline
000696304 994__ $$a92$$bISE