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000697945 020__ $$a9781493907151 $$qelectronic book
000697945 020__ $$a1493907158 $$qelectronic book
000697945 020__ $$z9781493907144
000697945 0247_ $$a10.1007/978-1-4939-0715-1$$2doi
000697945 035__ $$aSP(OCoLC)ocn878055861
000697945 035__ $$aSP(OCoLC)878055861
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000697945 049__ $$aISEA
000697945 050_4 $$aQH441
000697945 08204 $$a572.8/633$$223
000697945 1001_ $$aEl-Metwally, Sara,$$eauthor.
000697945 24510 $$aNext generation sequencing technologies and challenges in sequence assembly$$h[electronic resource]  /$$cSara El-Metwally, Osama M. Ouda, Mohamed Helmy.
000697945 264_1 $$aNew York, NY :$$bSpringer,$$c2014.
000697945 300__ $$a1 online resource (xii, 118 pages) :$$billustrations (some color).
000697945 336__ $$atext$$btxt$$2rdacontent
000697945 337__ $$acomputer$$bc$$2rdamedia
000697945 338__ $$aonline resource$$bcr$$2rdacarrier
000697945 4901_ $$aSpringerBriefs in Systems Biology,$$x2193-4746 ;$$v7
000697945 504__ $$aIncludes bibliographical references.
000697945 5050_ $$aBasics of Molecular Biology for Next-generation Sequencing -- Algorithms and Data Structures in Next-generation Sequencing -- First- and Next-generations Sequencing Models -- Next-generation Sequencing Platforms -- Challenges in Next-generation Sequencing Field -- New Horizons in Next-generation Sequencing -- Novel Next-generation Sequencing Applications -- Next-generation Sequence Assembly Overview -- Approaches and Challenges of Next-generation Sequence Assembly Stages -- Assessment of Next-generation Sequence Assembly -- Next-generation Sequence Assemblers -- Concluding Remarks.
000697945 506__ $$aAccess limited to authorized users.
000697945 520__ $$aThe introduction of Next Generation Sequencing (NGS) technologies resulted in a major transformation in the way scientists extract genetic information from biological systems, revealing limitless insight about the genome, transcriptome and epigenome of any species. However, with NGS, came its own challenges that require continuous development in the sequencing technologies and bioinformatics analysis of the resultant raw data and assembly of the full length genome and transcriptome. Such developments lead to outstanding improvements of the performance and coverage of sequencing and improved quality for the assembled sequences, nevertheless, challenges such as sequencing errors, expensive processing and memory usage for assembly and sequencer specific errors remains major challenges in the field. This book aims to provide brief overviews the NGS field with special focus on the challenges facing the NGS field, including information on different experimental platforms, assembly algorithms and software tools, assembly error correction approaches and the correlated challenges.
000697945 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed April 21, 2014).
000697945 650_0 $$aSequence alignment (Bioinformatics)
000697945 650_0 $$aNucleotide sequence.
000697945 7001_ $$aOuda, Osama M.,$$eauthor.
000697945 7001_ $$aHelmy, Mohamed,$$eauthor.
000697945 830_0 $$aSpringerBriefs in systems biology ;$$v7.$$x2193-4746
000697945 852__ $$bebk
000697945 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4939-0715-1$$zOnline Access
000697945 909CO $$ooai:library.usi.edu:697945$$pGLOBAL_SET
000697945 980__ $$aEBOOK
000697945 980__ $$aBIB
000697945 982__ $$aEbook
000697945 983__ $$aOnline
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