Small molecules in oncology [electronic resource] / Uwe M. Martens, editor.

Small molecules in oncology [electronic resource] / Uwe M. Martens, editor.

Second edition.

9783642544903 electronic book
3642544908 electronic book
9783642544897

Heidelberg : Springer, [2014]

©2014

English

1 online resource (xvi, 238 pages) : illustrations.

10.1007/978-3-642-54490-3 doi

RC268.4

616.994061

Extensive research into the molecular mechanisms of cancer has heralded a new age of targeted therapy. The field of personalized cancer therapy is now growing rapidly, and the progress being made will result in significant changes in the treatment algorithms for cancer patients. Numerous novel targets that are crucial for the survival of cancer cells can be attacked by small molecules such as protein tyrosine kinase inhibitors. This book, written by acknowledged experts, discusses in detail the most recent developments in targeted cancer therapy using small molecules. A wide range of small molecules is covered, including, in addition to tyrosine kinase inhibitors, mTOR, proteasome, and multikinase inhibitors, among others. For each molecule, aspects such as chemical structure, mechanism of action, drug targets, drug interactions, preclinical studies, clinical trials, treatment applications, and toxicity are discussed.

Includes bibliographical references.

Access limited to authorized users.

Description based on print version record.

Recent results in cancer research ; v.201.

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