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000706119 010__ $$a  2013037181
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000706119 020__ $$a0525953922$$qhardcover
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000706119 05004 $$aRA643.86.G2$$bH65 2014
000706119 08200 $$a614.5/993920943$$223
000706119 08204 $$a616.9792/060724$$223
000706119 1001_ $$aHolt, Nathalia,$$d1980-$$eauthor.
000706119 24510 $$aCured :$$bhow the Berlin patients defeated HIV and forever changed medical science /$$cNathalia Holt.
000706119 264_1 $$aNew York, New York :$$bDutton,$$c[2014]
000706119 300__ $$axxi, 313 pages ;$$c24 cm
000706119 336__ $$atext$$btxt$$2rdacontent
000706119 337__ $$aunmediated$$bn$$2rdamedia
000706119 338__ $$avolume$$bnc$$2rdacarrier
000706119 504__ $$aIncludes bibliographical references (pages 273-295) and index.
000706119 5050_ $$aA doctor, two patients, and some tests. The good doctor in denial ; A visit with the family doctor ; Death sentence? -- The disease, a drug, and its industry. Viral Trojan horse ; A weapon from the war on cancer ; The days of acting up ; Recognizing a global pandemic ; From the one percent ; But, Doctor, I don't feel sick ; The Delta 32 Mutation ; Calling all elite controllers ; Treatment in hiding -- Treating the Berlin patients. The second diagnosis ; The compassionate use exemption ; Three deadly diseases move in ; The comfort of family and strangers ; Timing ; Transplanting ; "Perhaps we have eradicated HIV" ; An unexciting recovery -- The cure. Trials ; Proof of principle ; The good doctor in court ; Not even surprising ; The promise kept ; A child cured-- so what? ; Zinc finger snap ; The abused, the respected, and relentless.
000706119 520__ $$aA young molecular biologist at the forefront of HIV research, Nathalia Holt tells the historic, multilayered, and compassionate story of two patients--each known in medical literature as the Berlin Patient--and their young research-minded doctors. The backdrop is nothing less than a revolution in cultural attitudes and medical thinking. These two patients' disparate cures came twelve years apart: the first in 1996 from an experimental cancer drug, the other in 2008 from a bone marrow transplant of cells with a particular genetic mutation. Holt connects the molecular dots of these two cases for the first time, providing insight into one of the most important medical breakthroughs of our generation.--From publisher description.
000706119 650_0 $$aHIV infections$$xTreatment$$zGermany$$zBerlin.
000706119 650_0 $$aGene therapy$$zGermany$$zBerlin$$xHistory.
000706119 85200 $$bgen$$hRA643.86.G2$$iH65$$i2014
000706119 909CO $$ooai:library.usi.edu:706119$$pGLOBAL_SET
000706119 980__ $$aBIB
000706119 980__ $$aBOOK