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000710712 020__ $$a9781493911547$$qelectronic book
000710712 020__ $$a1493911546$$qelectronic book
000710712 020__ $$z9781493911530
000710712 0247_ $$a10.1007/978-1-4939-1154-7$$2doi
000710712 035__ $$aSP(OCoLC)ocn889756557
000710712 035__ $$aSP(OCoLC)889756557
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000710712 24500 $$aGlycobiology of the nervous system$$h[electronic resource] /$$cRobert K. Yu, Cara-Lynne Schengrund, editors.
000710712 264_1 $$aNew York, NY :$$bSpringer,$$c2014.
000710712 300__ $$a1 online resource (xvii, 584 pages) :$$billustrations.
000710712 336__ $$atext$$btxt$$2rdacontent
000710712 337__ $$acomputer$$bc$$2rdamedia
000710712 338__ $$aonline resource$$bcr$$2rdacarrier
000710712 4901_ $$aAdvances in Neurobiology,$$x2190-5215 ;$$vvolume 9
000710712 500__ $$aIncludes index.
000710712 5050_ $$aIntroduction to the Complexity of Cell Surface and Tissue Matrix Glycoconjugates -- Introduction to Cells Comprising the Nervous System -- Synthesis, Processing, and Function of N-glycans in N-glycoproteins -- Synthesis of O-linked Glycoconjugates in the Nervous System -- Chemistry and Function of Glycosaminoglycans in the Nervous System -- Use of Glycan-targeted Antibodies/Lectins to Study the Expression/Function of Glycosyltransferases in the Nervous System -- From Mass Spectrometry-based Glycosylation Analysis to Glycomics and Glycoproteomic -- Structural Analysis of Oligosaccharides and Glycoconjugates using NMR -- Glycolipid and Glycoprotein Expression During Neural Development -- Gangliosides and Cell Surface Ganglioside Glycohydrolases in the Nervous System -- Role of Myelin-Associated Glycoprotein (Siglec-4a) in the Nervous System -- Role of Galactosylceramide and Sulfatide in Oligodendrocytes and CNS Myelin: Formation of a Glycosynapse -- Glycosignaling -- A General Review -- Glycosphingolipids in the Regulation of the Nervous System -- Glycobiology of Ion Transport in the Nervous System -- O-GlcNAcylation of Neuronal Proteins: Roles in Neuronal Functions and in Neurodegeneration -- N-glycosylation in Regulation of the Nervous System -- Roles of Carbohydrates in the Interaction of Pathogens with Neural Cells -- Glycoconjugate Changes in Aging and Age-related Diseases -- Gangliosides and Glycolipids in Neurodegenerative Disorders -- Glycosidases: Inborn Errors of Glycosphingolipid Catabolism -- Ganglioside Storage Diseases: On the Road to Management -- Dynamic Aspects of Neural Tumor Gangliosides -- Galectins and Neuroinflammation -- Glycoconjugates and Neuroimmunological Diseases.
000710712 506__ $$aAccess limited to authorized users.
000710712 520__ $$aA thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
000710712 588__ $$aDescription based on online resource; title from PDF title page (SpringerLink, viewed Sept. 2, 2014).
000710712 650_0 $$aGlycoconjugates.
000710712 650_0 $$aNeurobiology.
000710712 650_0 $$aNeurochemistry.
000710712 7001_ $$aYu, Robert K.,$$eeditor.
000710712 7001_ $$aSchengrund, Cara-Lynne,$$eeditor.
000710712 830_0 $$aAdvances in neurobiology ;$$vv.9.
000710712 85280 $$bebk$$hSpringerLink
000710712 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4939-1154-7$$zOnline Access
000710712 909CO $$ooai:library.usi.edu:710712$$pGLOBAL_SET
000710712 980__ $$aEBOOK
000710712 980__ $$aBIB
000710712 982__ $$aEbook
000710712 983__ $$aOnline
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