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000717138 019__ $$a899249038
000717138 020__ $$a9783319086750$$qelectronic book
000717138 020__ $$a3319086758$$qelectronic book
000717138 020__ $$z9783319086743
000717138 020__ $$z331908674X
000717138 0247_ $$a10.1007/978-3-319-08675-0$$2doi
000717138 035__ $$aSP(OCoLC)ocn895661136
000717138 035__ $$a717138
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000717138 050_4 $$aRS431.C23$$bC37 2014eb
000717138 08204 $$a615.3$$223
000717138 24500 $$aCarbohydrates as drugs$$h[electronic resource] /$$cPeter H. Seeberger, Christoph Rademacher, editors.
000717138 264_1 $$aCham :$$bSpringer,$$c[2014]
000717138 264_4 $$c©2014
000717138 300__ $$a1 online resource (vii, 237 pages) :$$billustrations.
000717138 336__ $$atext$$btxt$$2rdacontent
000717138 337__ $$acomputer$$bc$$2rdamedia
000717138 338__ $$aonline resource$$bcr$$2rdacarrier
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000717138 4901_ $$aTopics in medicinal chemistry ;$$v12
000717138 504__ $$aIncludes bibliographical references and index.
000717138 5050_ $$aCarbohydrate-Based Synthetic Chemistry in the Context of Drug Design -- Iminosugars: Therapeutic Applications and Synthetic Considerations -- Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs -- Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes -- Design, Synthesis, and Applications of Galectin Modulators in Human Health -- Discovery and Application of FimH Antagonists -- Carbohydrate-Based Anti-Virulence Compounds Against Chronic Pseudomonas aeruginosa Infections with a Focus on Small Molecules -- The Evolution of a Glycoconjugate Vaccine for Candida albicans.
000717138 506__ $$aAccess limited to authorized users.
000717138 520__ $$aMedicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.
000717138 588__ $$aDescription based on online resource ; title from PDF title page (viewed on January 8, 2015).
000717138 650_0 $$aCarbohydrate drugs.
000717138 650_0 $$aCarbohydrates$$xBiotechnology.
000717138 650_0 $$aDrug development.
000717138 650_0 $$aPharmaceutical chemistry.
000717138 7001_ $$aSeeberger, Peter H.,$$d1966-$$eeditor.
000717138 7001_ $$aRademacher, Christoph$$q(Christoph W.),$$eeditor.
000717138 77608 $$iPrint version:$$z9783319086743
000717138 830_0 $$aTopics in medicinal chemistry ;$$v12.
000717138 85280 $$bebk$$hSpringerLink
000717138 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-3-319-08675-0$$zOnline Access
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000717138 980__ $$aEBOOK
000717138 980__ $$aBIB
000717138 982__ $$aEbook
000717138 983__ $$aOnline
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