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000717258 019__ $$a895661024
000717258 020__ $$a9781493918560$$qelectronic book
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000717258 0247_ $$a10.1007/978-1-4939-1856-0$$2doi
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000717258 24500 $$aNeurobiological studies of addiction in chronic pain states$$h[electronic resource] /$$cedited by Carolyn A. Fairbanks, Thomas J. Martin, Ph.D.
000717258 264_1 $$aNew York, NY :$$bSpringer,$$c2014.
000717258 300__ $$a1 online resource (xii, 132 pages) :$$billustrations
000717258 336__ $$atext$$btxt$$2rdacontent
000717258 337__ $$acomputer$$bc$$2rdamedia
000717258 338__ $$aonline resource$$bcr$$2rdacarrier
000717258 4901_ $$aContemporary Clinical Neuroscience ;$$v17
000717258 500__ $$aIncludes index.
000717258 5050_ $$aOpioid and Non-Opioid Drug Responding Under States of Chronic Pain: A Timeline Spanning 1980 to Present Day -- Opioid Self-Administration in the Presence of Chronic Pain: Analgesia or Addiction -- The Influence of Pain on Reward Processing: Current Literature and Prospects -- Chronic Pain Stimuli Downregulate Mesolimbic Dopaminergic Transmission: Possible Mechanism of the Suppression of Opioid Reward -- Drug Addiction and Chronic Pain: A Review of Animal Models -- Biopharmaceutical Considerations of Opioid Analgesics in Models of Self-Administration: Review and Summary -- Prenatal Exposure to Opioids -- Opioids in an Evidence-Based World.
000717258 506__ $$aAccess limited to authorized users.
000717258 520__ $$aUsing rodent models, the contributors explore the basic neurobiology of the relationship among chronic pain, opioid pharmacology, and addiction. Combining various pain models with opioid self-administration and central administration pharmacotherapies allows researchers to answer important questions about: 1. The efficacy of opioid treatment under conditions of chronic pain of different etiology. 2. Alterations in the efficacy of opioid treatment under conditions of long-term opioid pharmacotherapy. 3. The potential for conversion or escalation of extra-analgesic motivation for opioid use beyond that required for pain relief. 4. The possibility of addiction development in chronic pain sufferers. Merging the field of pain researchers with that of addiction research has presented some unique challenges and this volume seeks to provide some guidance for future study design in addition to a summary of current findings in the area.
000717258 650_0 $$aMedicine.
000717258 650_0 $$aNeurosciences.
000717258 650_0 $$aPain medicine.
000717258 650_0 $$aLaboratory animals.
000717258 650_0 $$aChronic pain$$xPsychological aspects.
000717258 650_0 $$aAnalgesics.
000717258 7001_ $$aFairbanks, Carolyn A.,$$eeditor.
000717258 7001_ $$aMartin, Thomas J.,$$eeditor.
000717258 77608 $$iPrint version:$$z9781493918553
000717258 830_0 $$aContemporary clinical neuroscience ;$$v17.
000717258 85280 $$bebk$$hSpringerLink
000717258 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://dx.doi.org/10.1007/978-1-4939-1856-0$$zOnline Access
000717258 909CO $$ooai:library.usi.edu:717258$$pGLOBAL_SET
000717258 980__ $$aEBOOK
000717258 980__ $$aBIB
000717258 982__ $$aEbook
000717258 983__ $$aOnline
000717258 994__ $$a92$$bISE