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000723062 020__ $$a9783642404443$$qelectronic book
000723062 020__ $$a3642404448$$qelectronic book
000723062 020__ $$z9783642404436
000723062 0247_ $$a10.1007/978-3-642-40444-3$$2doi
000723062 035__ $$aSP(OCoLC)ocn863052848
000723062 035__ $$aSP(OCoLC)863052848
000723062 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDXCP$$dN$T$$dOCLCF$$dOCLCQ
000723062 049__ $$aISEA
000723062 050_4 $$aRM267
000723062 08204 $$a615.7/92$$223
000723062 24500 $$aAntimicrobial compounds$$h[electronic resource] :$$bcurrent strategies and new alternatives /$$cTomás G. Villa, Patricia Veiga-Crespo, editors.
000723062 264_1 $$aHeidelberg :$$bSpringer,$$c2014.
000723062 300__ $$a1 online resource (xvi, 316 pages) :$$billustrations (some color)
000723062 336__ $$atext$$btxt$$2rdacontent
000723062 337__ $$acomputer$$bc$$2rdamedia
000723062 338__ $$aonline resource$$bcr$$2rdacarrier
000723062 500__ $$aIncludes index.
000723062 5050_ $$aStrategies for the design and discovery of novel antibiotics using genetic engineering and genome mining -- X-ray and Neutron Scattering Foundations for the Research in Antimicrobials -- Antibacterial, Antiviral and Antifungal Activity of Essential Oils: Mechanisms and Applications -- New antimicrobial agents of plant origin -- Advances in beta-lactam antibiotics -- The Cornerstone of Nucleic Acid-affecting Antibiotics in Bacteria -- Genetic analysis and manipulation of polyene antibiotic gene clusters as a way to produce more effective antifungal compounds -- Enzybiotics: The rush towards prevention and control of multi-resistant bacteria (MRB) -- New cell wall-affecting antifungal antibiotics -- Perspectives in the research on Antimicrobial peptides -- Glycopeptides and bacterial cell walls.
000723062 506__ $$aAccess limited to authorized users.
000723062 520__ $$aSince penicillin and salvarsan were discovered, a number of new drugs to combat infectious diseases have been developed, but at the same time, the number of multi-resistant microorganism strains is increasing. Thus, the design of new and effective antibacterial, antiviral and antifungal agents will be a major challenge in the next years. This book reviews the current state-of-the-art in antimicrobial research and discusses new strategies for the design and discovery of novel therapies. Topics covered include the use of genetic engineering, genome mining, manipulation of gene clusters, X-ray and neutron scattering as well as the antimicrobial effects of essential oils, antimicrobial agents of plant origin, beta-lactam antibiotics, antimicrobial peptides, and cell-wall-affecting antifungal antibiotics.
000723062 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 21, 2013).
000723062 650_0 $$aAnti-infective agents.
000723062 7001_ $$aVilla, Tomás G.,$$eeditor.
000723062 7001_ $$aVeiga-Crespo, Patricia,$$eeditor.
000723062 852__ $$bebk
000723062 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-642-40444-3$$zOnline Access$$91397441.1
000723062 909CO $$ooai:library.usi.edu:723062$$pGLOBAL_SET
000723062 980__ $$aEBOOK
000723062 980__ $$aBIB
000723062 982__ $$aEbook
000723062 983__ $$aOnline
000723062 994__ $$a92$$bISE