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000723899 020__ $$a9781493917617$$qelectronic book
000723899 020__ $$a1493917617$$qelectronic book
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000723899 0247_ $$a10.1007/978-1-4939-1761-7$$2doi
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000723899 24500 $$aSynaptic tagging and capture$$h[electronic resource] :$$bfrom synapses to behavior /$$cSreedharan Sajikumar, editor.
000723899 264_1 $$aNew York, NY :$$bSpringer,$$c[2015]
000723899 264_4 $$c©2015
000723899 300__ $$a1 online resource (xxiii, 263 pages) :$$billustrations.
000723899 336__ $$atext$$btxt$$2rdacontent
000723899 337__ $$acomputer$$bc$$2rdamedia
000723899 338__ $$aonline resource$$bcr$$2rdacarrier
000723899 504__ $$aIncludes bibliographical references and index.
000723899 5050_ $$aPref ace; Part I: Introduction; Acknowledgements; References; Part II: Introduction; Reference; Contents; Contributors; About the Editor; Part I: Cellular and Molecular Aspects of Synaptic Tagging and Capture; Chapter 1: Differential Role of CaMK in Synaptic Tagging and Capture; 1.1 Introduction; 1.2 STC Protocols as Tools to Elucidate the Role of Molecules in Synaptic Plasticity; 1.3 Roles of CaMKII and CaMKK in STC; References; Chapter 2: Compartmentalization of Synaptic Tagging and Capture; 2.1 Why Compartmentalization?; 2.2 STC and Compartmentalization; 2.3 Making a Compartment
000723899 5058_ $$a2.4 Consolidating a Compartment2.5 Functional Compartmentalization; 2.6 Compartmental Computation; 2.7 Compartmental Encoding; 2.8 Experience-Dependent Compartmentalization; 2.9 Multiple Levels of Integration of Information; References; Chapter 3: Synaptic Cooperation and Competition: Two Sides of the Same Coin?; 3.1 Introduction; 3.2 Synaptic Cooperation and Competition in a Developing Nervous System; 3.3 Synaptic Cooperation and Competition During LTP; 3.4 Synaptic Cooperation and Competition During LTP Maintenance
000723899 5058_ $$a3.5 Synaptic Cooperation in the Lateral Nucleus of the Amygdala: Link to Behavior?3.6 Conclusion Remarks; References; Chapter 4: Neuropsin-Dependent and -Independent Synaptic Tagging and Modulation of Long-Term Potentiation: A Quest for the Associated Signaling Pathway(s); 4.1 Introduction; 4.2 E-LTP-Related Signaling Molecules That Are Modulated by Weak Stimulation; 4.3 The Extracellular Protease Neuropsin Contributes to E-LTP; 4.4 Neuropsin-Dependent and Independent Synaptic Tagging; 4.5 Conclusions; References; Chapter 5: PKA Anchoring and Synaptic Tagging and Capture; 5.1 Introduction
000723899 5058_ $$a5.2 The Role of PKA in Synaptic Plasticity and Memory Formation5.3 The Requirement for PKA in Synaptic Tagging and Capture; 5.4 Other Potential Tagging Mechanisms Possibly Mediated by PKA; 5.5 Plasticity-Related Products; 5.6 The Role of PKA Anchoring in Synaptic Plasticity and Memory Formation; 5.7 Examples of AKAPs Modulating Neuronal Function; 5.8 PKA-Centric Unified Model of Synaptic Tagging and Capture; 5.9 Future Directions; References; Chapter 6: Activity-Dependent Protein Transport as a Synaptic Tag; 6.1 Relevance of Synaptic Tagging in Late Plasticity
000723899 5058_ $$a6.1.1 Synaptic Tagging as an Input-Specificity Mechanism of Late Plasticity6.1.2 Two Possibilities of Synaptic Tagging Action; 6.2 Strategy to Reach the Cell Biological Activity of Synaptic Tagging; 6.2.1 Advantage and Limitations of Two-Pathway Protocol; 6.2.2 Controlled Transport Across Dendrite-Spine Boundary; 6.2.3 Critical Assumptions of Our Hypothesis; 6.2.4 Use of Vesl-1S for the Tracer PRP; 6.3 Results; 6.3.1 Activity-Dependent Regulation of Spine Translocation of Vesl-1S/Homer-1a Protein as a Synaptic Tagging; 6.3.2 Molecular Mechanisms Underlying VE Protein Transport to Spine
000723899 506__ $$aAccess limited to authorized users.
000723899 520__ $$aServes as a comprehensive introduction and overview of synaptic tagging and capture (STC) and covers the topic from molecular and cellular aspects to behavior.  Circa 15 years ago the STC model was proposed to provide a conceptual basis for how short-term memories are transformed into long-term memories. Though the hypothesis remains unconfirmed due to technological limitations, the model is well consolidated and generally accepted in the field. Various researchers have investigated the cellular mechanisms for the formation of long-term memory using the STC model, but this is the first book-l.
000723899 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed October 20, 2014).
000723899 650_0 $$aSynapses.
000723899 650_0 $$aMemory.
000723899 650_0 $$aNeurosciences.
000723899 7001_ $$aSajikumar, Sreedharan,$$eeditor.
000723899 77608 $$iPrint version:$$aSajikumar, Sreedharan$$tSynaptic Tagging and Capture : From Synapses to Behavior$$dNew York, NY : Springer New York,c2014$$z9781493917600
000723899 852__ $$bebk
000723899 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4939-1761-7$$zOnline Access$$91397441.1
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