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Preface 1; Preface 2; Contents; Contributors; 1: Introduction; 2: Histamine and Biogenic Amines; 2.1 Histamine; 2.1.1 Physiological (Natural) Effects; 2.2 Diamine Oxidase; 2.3 Determination of Histamine, Diamine Oxidase, and Tryptase; 2.4 Histamine Intolerance; 2.4.1 What Are the Actual Symptoms?; 2.5 Diagnosis of Histamine Intolerance; 2.5.1 Differential Diagnosis; 2.5.2 Diagnosis; 2.5.2.1 Medical History; 2.5.2.2 Negative Histamine Provocation; 2.5.2.3 Determination of Histamine and Methylhistamine in Urine; 2.5.2.4 Histamine in Stool; 2.6 Origin of Histamine; 2.7 Histamine Levels in Food

2.7.1 Cheese2.7.2 Chocolate; 2.7.3 Meat and Meat Products; 2.7.4 Fish and Fish Products; 2.7.5 Vegetables, Fruit, and Nuts; 2.7.6 Other Biogenic Amines in Food, Histamine Liberators; 2.8 Histamine in Alcoholic Beverages; 2.8.1 Red Wine; 2.8.2 White Wine; 2.8.3 Sparkling Wines and Champagne; 2.8.4 Beer; 2.8.5 Hard Liquor; 2.8.6 Why Does Histamine in Alcoholic Beverages Have a Particularly Strong Effect?; 2.8.7 Other Causes of Wine and Alcohol Intolerance; 2.9 How It All Started: Wine Intolerance; 2.10 Differential Diagnosis: Food Allergy (FA); 2.10.1 Primary ("Genuine") Food Allergy (FA)

2.10.2 Secondary or Associated Food Allergy (FA)References; Histamine; Diamine Oxidase; Histamine Intolerance; Diagnosis of Histamine Intolerance; Origin of Histamine; Histamine Levels in Food; Histamine in Alcoholic Beverages; How It All Started: Wine Intolerance; 3: Disease Patterns in the Presence of Histamine Intolerance; 3.1 Headache; 3.2 Blocked or Runny Nose; 3.2.1 Allergic Rhinitis; 3.2.2 Anatomical Changes in the Nose, Nasal Polyps, and Adenoids; 3.2.3 Chronic Inflammation of the Paranasal Sinuses and Vasomotor Rhinitis; 3.3 Bronchial Asthma; 3.3.1 Asthma and Inhalant Allergens

3.3.2 House Dust Mites3.3.3 Animal Allergens; 3.3.4 Pollen; 3.3.5 Asthma and Food; 3.4 Cardiac Arrhythmia; 3.5 Gastric Symptoms; 3.6 Diarrhea and Allergic Gastrointestinal Diseases; 3.6.1 Mechanisms and Classification of Histamine Intolerance (HIT); 3.6.2 GI-Mediated Allergies and Histamine Intolerance; 3.6.2.1 Diagnostic Investigation; 3.6.2.2 Additional Modifying Factors; 3.6.2.3 Important Aspects of Food; 3.6.2.4 Specific Therapy; 3.6.2.5 Unspecific Supportive Therapy; 3.6.2.6 Supplementary Nutrition Therapy; 3.6.2.7 Stagewise Drug Therapy; 3.6.2.8 Mast Cell Stabilizers and Antihistamines

3.6.2.9 Ketotifen and Older Antihistamines3.6.2.10 Newer Nonsedating Antihistamines; 3.6.2.11 Further Drug-Based Therapy Options; 3.7 Irritable Bowel Syndrome; 3.8 Low Blood Pressure (Hypotension); 3.9 Urticaria; 3.10 Mastocytosis and Mast Cell Activation Syndrome; 3.10.1 Definition; 3.10.2 Classification of Various Forms of Mastocytosis; 3.10.3 Symptoms of Mastocytosis; 3.10.4 Diagnostic Investigation of Mastocytosis; 3.10.5 Treatment of Mastocytosis; 3.11 Histamine Metabolism in Chronic Inflammatory Bowel Disease; References; Headache; Bronchial Asthma; Cardiac Arrhythmia; Gastric Symptoms

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