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Subunit vaccine delivery [electronic resource] / Camilla Foged, Thomas Rades, Yvonne Perrie, Sarah Hook, editors.

Foged, Camilla, editor.
2015
RM281
Available Online
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Title
Subunit vaccine delivery [electronic resource] / Camilla Foged, Thomas Rades, Yvonne Perrie, Sarah Hook, editors.
ISBN
9781493914173 electronic book
1493914170 electronic book
9781493914166
DOI
https://doi.org/10.1007/978-1-4939-1417-3
Published
New York : Springer, 2015.
Language
English
Description
1 online resource (xiv, 431 pages) : illustrations (some color).
Item Number
10.1007/978-1-4939-1417-3 doi
Call Number
RM281
Dewey Decimal Classification
615.3/72
Summary
This comprehensive volume compiles the concepts essential for the understanding of the pharmaceutical science and technology associated with the delivery of subunit vaccines. Twenty-one chapters are divided into four main parts: (I) Background; (2) Delivery Systems for Subunit Vaccines; (3) Delivery Routes, Devices and Dosage Forms; and (4) Pharmaceutical Analysis and Quality Control of Vaccines. Part one provide a basic background with respect to immunology and general vaccine classification. In part two, it presents representative types of vaccine delivery systems individually with focus on the physicochemical properties of the systems and their significance for the immune response they stimulate. These delivery systems include aluminum adjuvants, emulsions, liposomes, bilosomes, cubosomes/hexosomes, ISCOMs, virus-like particles, polymeric nano- and microparticles, gels, implants and cell-based delivery systems. Following these chapters, part three addresses the challenges associated with vaccine delivery via specific routes of administration?in particular subcutaneous, intramuscular, oral, nasal, pulmonary, transdermal and vaginal administration. Furthermore, the specific administration routes are discussed in combination with device technologies relevant for the respective routes as well as dosage forms appropriate for the device technology. Finally, the fourth part concerns pharmaceutical analysis and quality control of subunit vaccines.
Note
Includes index.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed January 15, 2015).
Added Author
Foged, Camilla, editor.
Series
Advances in delivery science and technology.
Available in Other Form
Print version: 9781493914166
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1 Immunological Background
2 Classification of Vaccines
3 Aluminum Adjuvants
Basic Concepts and Progress in Understanding
4 Emulsions as Vaccine Adjuvants
5 The application of liposomes as vaccine adjuvants
6 Developing Bilayer-based Delivery Systems for Oral Delivery of Subunit Vaccines
7 Cubosomes ? Structure, Preparation and Use as an Antigen Delivery System
8 ISCOMs as a Vaccine Delivery System
9 Virus-like Particles, a Versatile Subunit Vaccine Platform
10 Polymeric Particulates for Subunit Vaccine Delivery
11 Gels as Vaccine Delivery Systems
12 Implants as Sustained Release Delivery Devices for Vaccine Antigens
13 Dendritic Cell-based Vaccines
14 Parenteral Vaccine Administration ? Tried and True
15 Nasal Administration of Vaccines
16 Pulmonary Administration of Subunit Vaccines
17 Vaginal Delivery of Subunit Vaccines
18 Transcutaneous Administration
19 Pharmaceutical Analysis and Quality Control of Vaccines
20 The Physical Analysis of Vaccines
21 Characterizing the Association between Antigens and Adjuvants.

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