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000724536 019__ $$a899000580$$a908088379
000724536 020__ $$a9783319100128$$qelectronic book
000724536 020__ $$a3319100122$$qelectronic book
000724536 020__ $$z9783319100111
000724536 0247_ $$a10.1007/978-3-319-10012-8$$2doi
000724536 035__ $$aSP(OCoLC)ocn896825004
000724536 035__ $$aSP(OCoLC)896825004$$z(OCoLC)899000580$$z(OCoLC)908088379
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000724536 24500 $$aInflammatory disorders$$h[electronic resource] /$$cMieczyslaw Pokorski, editor.
000724536 264_1 $$aCham :$$bSpringer,$$c2015.
000724536 300__ $$a1 online resource (x, 67 pages) :$$billustrations.
000724536 336__ $$atext$$btxt$$2rdacontent
000724536 337__ $$acomputer$$bc$$2rdamedia
000724536 338__ $$aonline resource$$bcr$$2rdacarrier
000724536 4901_ $$aAdvances in Experimental Medicine and Biology,$$x0065-2598 ;$$vvolume 839.$$aNeuroscience and respiration
000724536 500__ $$aIncludes index.
000724536 504__ $$aIncludes bibliographical references and index.
000724536 5050_ $$aInhaled Corticosteroids Increase Siglec-5/14 Expression in Sputum Cells of COPD Patients -- Tregs and HLA-DR Expression in Sputum Cells of COPD Patients Treated with Tiotropium and Formoterol -- Inhalation of Macrolides: A Novel Approach to Treatment of Pulmonary Infections -- Influence of Denture Plaque Biofilm on Oral Mucosal Membrane in Patients with Chronic Obstructive Pulmonary Disease -- Biophysical Activity of Animal-Derived Exogenous Surfactants Mixed with Rifampicin -- Organic Changes in the Central Nervous System in Children on Chronic Inhaled Corticosteroid Therapy -- Stem Cell Experiments Moves into Clinic: New Hope for Children with Bronchopulmonary Dysplasia -- Soluble Ligand CD40 and Uric Acid as Markers of Atheromatosis in Patients with Obstructive Sleep Apnea -- Carotid Artery Intima-Media Thickness in Hypertensive Patients with Obstructive Sleep Apnea.
000724536 506__ $$aAccess limited to authorized users.
000724536 520__ $$aThe mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens and thus in lung tissue damage of chronic inflammation. The results help understand the mechanisms of action of common drugs used in COPD, such as formoterol, tiotropium, or corticosteroids, and point to novel drug targets. The chapters also deal with brain damaging effects, by far unrecognized, of inhaled corticosteroid therapy, a time-proven management of chronic inflammatory airway conditions; asthma being a case in point. Novel methods, likely less producing side effects, of macrolide antibiotics administration by inhalation are discussed, emphasizing not only bacteriostatic but also anti-inflammatory action.
000724536 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed January 22, 2015).
000724536 650_0 $$aInflammation.
000724536 7001_ $$aPokorski, Mieczyslaw,$$eeditor.
000724536 77608 $$iPrint version:$$tInflammatory disorders.$$dCham, Switzerland : Springer, c2015$$z9783319100111$$w2014957144
000724536 830_0 $$aAdvances in experimental medicine and biology ;$$vv. 839.
000724536 830_0 $$aAdvances in experimental medicine and biology.$$pNeuroscience and respiration.
000724536 852__ $$bebk
000724536 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-10012-8$$zOnline Access$$91397441.1
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000724536 983__ $$aOnline
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