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000724619 019__ $$a900323857$$a908041796$$a908085120
000724619 020__ $$a9783662450246$$qelectronic book
000724619 020__ $$a3662450240$$qelectronic book
000724619 020__ $$z9783662450239
000724619 0247_ $$a10.1007/978-3-662-45024-6$$2doi
000724619 035__ $$aSP(OCoLC)ocn897377107
000724619 035__ $$aSP(OCoLC)897377107$$z(OCoLC)900323857$$z(OCoLC)908041796$$z(OCoLC)908085120
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000724619 049__ $$aISEA
000724619 050_4 $$aQR189$$b.V33 2015eb
000724619 08204 $$a615/.372$$223
000724619 24500 $$aVaccine analysis$$h[electronic resource] :$$bstrategies, principles, and control /$$cBrian K. Nunnally, Vincent E. Turula, Robert D. Sitrin, editors.
000724619 264_1 $$aHeidelberg :$$bSpringer,$$c[2015]
000724619 300__ $$a1 online resource (xii, 665 pages) :$$billustrations (some color)
000724619 336__ $$atext$$btxt$$2rdacontent
000724619 337__ $$acomputer$$bc$$2rdamedia
000724619 338__ $$aonline resource$$bcr$$2rdacarrier
000724619 347__ $$atext file$$bPDF$$2rda
000724619 504__ $$aIncludes bibliographical references and index.
000724619 5050_ $$aLive Attenuated Viral Vaccines -- Inactivated Viral Vaccines -- Recombinant Virus Like Particle Protein Vaccines -- Analysis of influenza vaccines -- Live-attenuated and inactivated whole-cell bacterial vaccines -- Analytical control strategy of bacterial subunit vaccines -- Bacterial Polysaccharide Vaccines: Analytical Perspectives -- Glycoconjugate vaccines -- Vaccines in research and development: new production platforms and new biomolecular entities for new needs -- Role of Analytics In Viral Safety -- Deep Sequencing Applications for Vaccine Development and Safety -- Quality-by-design: As related to analytical concepts, control and qualification -- Vaccine Potency Assays -- Establishing a Shelf-life and Setting Lot-release Specifications -- Vaccine Reference Standards -- Lot Release of Vaccines by Regulatory Authorities and Harmonization of Testing Requirements -- Dendritic cell targeting vaccines.
000724619 506__ $$aAccess limited to authorized users.
000724619 520__ $$aThis book is an indispensable tool for anyone involved in the research, development, or manufacture of new or existing vaccines. It describes a wide array of analytical and quality control technologies for the diverse vaccine modalities. Topics covered include the application of both classical and modern bio-analytical tools; procedures to assure safety and control of cross contamination; consistent biological transition of vaccines from the research laboratory to manufacturing scale; whole infectious attenuated organisms, such as live-attenuated and inactivated whole-cell bacterial vaccines and antiviral vaccines using attenuated or inactivated viruses; principles of viral inactivation and the application of these principles to vaccine development; recombinant DNA approaches to produce modern prophylactic vaccines; bacterial subunit, polysaccharide and glycoconjugate vaccines; combination vaccines that contain multiple antigens as well as regulatory requirements and the hurdles of licensure.
000724619 588__ $$aOnline resource; title from PDF title page (viewed January 30, 2015).
000724619 650_0 $$aVaccines$$xTesting.
000724619 650_0 $$aVaccines industry$$xQuality control.
000724619 650_0 $$aAnalytical chemistry.
000724619 7001_ $$aNunnally, Brian K.,$$eeditor.
000724619 7001_ $$aTurula, Vincent E.,$$eeditor.
000724619 7001_ $$aSitrin, Robert D.,$$eeditor.
000724619 77608 $$iPrint version:$$z9783662450239
000724619 852__ $$bebk
000724619 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-662-45024-6$$zOnline Access$$91397441.1
000724619 909CO $$ooai:library.usi.edu:724619$$pGLOBAL_SET
000724619 980__ $$aEBOOK
000724619 980__ $$aBIB
000724619 982__ $$aEbook
000724619 983__ $$aOnline
000724619 994__ $$a92$$bISE