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000724778 020__ $$a9783658082697$$qelectronic book
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000724778 0247_ $$a10.1007/978-3-658-08269-7$$2doi
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000724778 049__ $$aISEA
000724778 050_4 $$aQP552.T68$$bW55 2015eb
000724778 08204 $$a572.8/845$$223
000724778 1001_ $$aWill, Thorsten,$$eauthor.
000724778 24510 $$aPredicting transcription factor complexes$$h[electronic resource] :$$ba novel approach to data integration in systems biology /$$cThorsten Will.
000724778 264_1 $$aWiesbaden, [Germany] :$$bSpringer Spektrum,$$c[2015]
000724778 264_4 $$c©2015
000724778 300__ $$a1 online resource :$$billustrations.
000724778 336__ $$atext$$btxt$$2rdacontent
000724778 337__ $$acomputer$$bc$$2rdamedia
000724778 338__ $$aonline resource$$bcr$$2rdacarrier
000724778 4901_ $$aBestMasters
000724778 504__ $$aIncludes bibliographical references (pages 121-142).
000724778 5050_ $$aProtein Complex Prediction -- Protein-Protein Interaction Networks -- Domain-Domain Interaction Networks -- Combinatorial Algorithms -- Algorithm Engineering.
000724778 506__ $$aAccess limited to authorized users.
000724778 520__ $$aIn his master thesis Thorsten Will proposes the substantial information content of protein complexes involving transcription factors in the context of gene regulatory networks, designs the first computational approaches to predict such complexes as well as their regulatory function and verifies the practicability using data of the well-studied yeast S.cereviseae. The novel insights offer extensive capabilities towards a better understanding of the combinatorial control driving transcriptional regulation. Contents Protein Complex Prediction Protein-Protein Interaction Networks Domain-Domain Interaction Networks Combinatorial Algorithms Algorithm Engineering Target Groups Computational biologists and biologists working with gene regulatory networks Computer scientists interested in biological issues The Author Currently, the author is pursuing his Ph.D. at the Center for Bioinformatics in Saarbrücken, Germany.
000724778 650_0 $$aTranscription factors.
000724778 650_0 $$aGenetic regulation.
000724778 650_0 $$aBioinformatics.
000724778 650_0 $$aProteins$$xConformation.
000724778 77608 $$iPrint version:$$tPredicting Transcription Factor Complexes$$z9783658082680$$w(OCoLC)895729964
000724778 830_0 $$aBestMasters.
000724778 852__ $$bebk
000724778 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-658-08269-7$$zOnline Access$$91397441.1
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000724778 980__ $$aEBOOK
000724778 980__ $$aBIB
000724778 982__ $$aEbook
000724778 983__ $$aOnline
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