000725628 000__ 03393cam\a2200505Ii\4500 000725628 001__ 725628 000725628 005__ 20230306140649.0 000725628 006__ m\\\\\o\\d\\\\\\\\ 000725628 007__ cr\cn\nnnunnun 000725628 008__ 150213t20152015sz\a\\\\ob\\\\001\0\eng\d 000725628 019__ $$a908091221 000725628 020__ $$a9783319148304$$qelectronic book 000725628 020__ $$a3319148303$$qelectronic book 000725628 020__ $$z9783319148298 000725628 0247_ $$a10.1007/978-3-319-14830-4$$2doi 000725628 035__ $$aSP(OCoLC)ocn903357062 000725628 035__ $$aSP(OCoLC)903357062$$z(OCoLC)908091221 000725628 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dDKU$$dUPM$$dBTCTA$$dIDEBK$$dCOO$$dOCLCF$$dE7B$$dCDX$$dYDXCP$$dEBLCP 000725628 049__ $$aISEA 000725628 050_4 $$aRA777.6 000725628 08204 $$a613.0438$$223 000725628 24500 $$aNutrition, exercise and epigenetics$$h[electronic resource] :$$bageing interventions /$$cByung Pal Yu, editor. 000725628 264_1 $$aCham :$$bSpringer,$$c[2015] 000725628 264_4 $$c©2015 000725628 300__ $$a1 online resource :$$billustrations. 000725628 336__ $$atext$$btxt$$2rdacontent 000725628 337__ $$acomputer$$bc$$2rdamedia 000725628 338__ $$aonline resource$$bcr$$2rdacarrier 000725628 4901_ $$aHealthy ageing and longevity ;$$vvolume 2 000725628 504__ $$aIncludes bibliographical references and index. 000725628 5050_ $$aPreface -- Epigenetics and Nutrition -- Calorie restriction as a potent epigenetic modifier -- Anti-inflammatory action of calorie restriction for aging intervention -- Hormonal influence and modulation on aging -- Epigenetic modification by exercise -- Physiological bases and underlying mechanisms of exercise -- Sarcopenia and its intervention -- Nutritional impacts on osteopenia and osteoporosis -- Nutritional interventions for cardiac aging and age-related cardiovascular diseases -- Nutritional influence on aging brain -- Mechanistic bases of calorie restriction mimetics -- Lessons learned from calorie restricted non-human primate research. 000725628 506__ $$aAccess limited to authorized users. 000725628 520__ $$aThis book focuses on the three most important aspects of ageing research: nutrition, physical exercise and epigenetics. The contributors discuss ways that age-related epigenetic imprints such as DNA methylation and histone acetylation are modified by these two interventions. The emphasis on epigenetics helps to illuminate the underlying mechanisms of anti-ageing interventions, as ageing and disease are predominately epigenetic phenomena. Among the highlights are chapter-length discussion of such topics as: ℗ℓhow anti-inflammatory action of calorie restriction underlies the retardation of ageing and age-related diseases (Chapter 3); epigenetic modification of gene expression by exercise (Chapter 5); the role of functional foods and their bioactive components in bone health (Chapter 8); and an account of the first decade of a study of calorie restriction in nonhuman primates, conducted by the National Institute on Ageing. ℗ℓ 000725628 588__ $$aDescription based on online resource; title from PDF title page (viewed February 18, 2015). 000725628 650_0 $$aAging$$xHealth aspects. 000725628 650_0 $$aEpigenetics. 000725628 650_0 $$aNutrition. 000725628 650_0 $$aExercise. 000725628 7001_ $$aYu, Byung Pal,$$eeditor. 000725628 77608 $$iPrint version:$$z9783319148298 000725628 830_0 $$aHealthy ageing and longevity ;$$vv. 2. 000725628 85280 $$bebk$$hSpringerLink 000725628 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-14830-4$$zOnline Access$$91397441.1 000725628 909CO $$ooai:library.usi.edu:725628$$pGLOBAL_SET 000725628 980__ $$aEBOOK 000725628 980__ $$aBIB 000725628 982__ $$aEbook 000725628 983__ $$aOnline 000725628 994__ $$a92$$bISE