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000725697 019__ $$a908041881
000725697 020__ $$a9783319143408$$qelectronic book
000725697 020__ $$a3319143409$$qelectronic book
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000725697 035__ $$aSP(OCoLC)ocn903644033
000725697 035__ $$aSP(OCoLC)903644033$$z(OCoLC)908041881
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000725697 0411_ $$aeng$$hfre
000725697 049__ $$aISEA
000725697 050_4 $$aRC268.5$$b.R63 2015eb
000725697 08204 $$a571.9/78$$223
000725697 1001_ $$aRobert, Jacques,$$cM.D.,$$eauthor.
000725697 24510 $$aTextbook of cell signalling in cancer$$h[electronic resource] :$$ban educational approach /$$cJacques Robert.
000725697 264_1 $$aCham :$$bSpringer,$$c2015.
000725697 300__ $$a1 online resource (xxiii, 328 pages) :$$billustrations.
000725697 336__ $$atext$$btxt$$2rdacontent
000725697 337__ $$acomputer$$bc$$2rdamedia
000725697 338__ $$aonline resource$$bcr$$2rdacarrier
000725697 500__ $$a"Updated translation from the French language edition "Signalisation cellulaire et cancer" by J. Robert ©Springer-Verlag France, Paris, 2010."
000725697 504__ $$aIncludes bibliographical references.
000725697 506__ $$aAccess limited to authorized users.
000725697 520__ $$aThis book provides a simplified, yet comprehensive, overview of the signalling pathways operating between and inside cells, which will help younger oncologists find their way in the labyrinth of signalling pathways and in the multitude of signals and signal receptors, transducers and effectors that contribute to oncogenesis. This comprehensive reference text is based on the masterℓ́ℓs courses delivered by Prof. Jacques Robert to graduate students at the University of Bordeaux, France. It includes a large number of colour schemas and figures that have been improved year after year for educational purposes. Signalling pathways are described individually and in depth, but without ignoring the multiplicity of interconnections and crosstalk. The presentation of each pathway is followed by a brief description of the alterations found in cancers as well as of the targeted pharmacological approaches that can be used to prevent or overcome the consequences of these oncogenic alterations. The basic mechanisms of molecular biology at the DNA replication, RNA transcription and protein activity levels are presented in a series of didactic annexes, enabling readers to better understand the alterations in signalling pathways.
000725697 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed February 25, 2015).
000725697 650_0 $$aCarcinogenesis.
000725697 650_0 $$aCellular signal transduction.
000725697 650_0 $$aCancer$$xMolecular aspects.
000725697 852__ $$bebk
000725697 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-14340-8$$zOnline Access$$91397441.1
000725697 909CO $$ooai:library.usi.edu:725697$$pGLOBAL_SET
000725697 980__ $$aEBOOK
000725697 980__ $$aBIB
000725697 982__ $$aEbook
000725697 983__ $$aOnline
000725697 994__ $$a92$$bISE