000726004 000__ 03768cam\a2200517Ii\4500 000726004 001__ 726004 000726004 005__ 20230306140708.0 000726004 006__ m\\\\\o\\d\\\\\\\\ 000726004 007__ cr\cn\nnnunnun 000726004 008__ 150312t20152015nyu\\\\\ob\\\\001\0\eng\d 000726004 019__ $$a908097399 000726004 020__ $$a9781493924325$$qelectronic book 000726004 020__ $$a149392432X$$qelectronic book 000726004 020__ $$z9781493924318 000726004 0247_ $$a10.1007/978-1-4939-2432-5$$2doi 000726004 035__ $$aSP(OCoLC)ocn904755652 000726004 035__ $$aSP(OCoLC)904755652$$z(OCoLC)908097399 000726004 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dBTCTA$$dIDEBK$$dE7B$$dCOO$$dYDXCP$$dCDX$$dEBLCP 000726004 049__ $$aISEA 000726004 050_4 $$aRC606.6 000726004 08204 $$a616.979206$$223 000726004 24500 $$aGene therapy for HIV and chronic infections$$h[electronic resource] /$$cBen Berkhout, Hildegund C.J. Ertl, Marc S. Weinberg, editors. 000726004 2463_ $$aGene therapy for human immunodeficiency virus and chronic infections 000726004 264_1 $$aNew York :$$bSpringer,$$c[2015] 000726004 264_4 $$c©2015 000726004 300__ $$a1 online resource. 000726004 336__ $$atext$$btxt$$2rdacontent 000726004 337__ $$acomputer$$bc$$2rdamedia 000726004 338__ $$aonline resource$$bcr$$2rdacarrier 000726004 4901_ $$aAdvances in experimental medicine and biology ;$$v848 000726004 504__ $$aIncludes bibliographical references and index. 000726004 5050_ $$aGene Therapies for Hepatitis C Virus -- Recent Advances in Use of Gene Therapy to Treat Hepatitis B Virus Infection -- U1interference (U1i) for antiviral approaches -- Gene therapy strategies to block HIV-1 replication by RNA interference -- HIV and Ribozymes -- Editing CCR5: a novel approach to HIV gene therapy -- Synthetic DNA approach to Cytomegalovirus vaccine/immune therapy -- Vector-mediated antibody gene transfer for infectious diseases -- HIV latency and the non-coding RNA therapeutic landscape -- C peptides as entry inhibitors for gene therapy -- Aptamer-siRNA chimeras for HIV . 000726004 506__ $$aAccess limited to authorized users. 000726004 520__ $$aThis volume examines gene therapy and gene transfer approaches to preventing or treating chronic virus infections, focusing on the Big Three viral pathogens- HIV, hepatitis B virus (HBV), and hepatitis C virus (HCV). It explores molecular antiviral strategies, including RNA interference, aptamer-siRNA chimeras, U1i interference, editing CCR5, alternative genetic vaccination by intramuscular gene transfers of virus vectors, and HIV latency in the context of non-coding RNA. This title is a volume of the American Society of Gene and Cell Therapy, a sub-series of the highly successful Advances in Experimental Medicine and Biology. In eleven illustrated chapters, leading international researchers contextualize the structure, operation, and impact of pathogens; examine the existing genetic and molecular research; and extract possible methods of preventing and treating chronic viral infections while evaluating the current body of knowledge. Authoritative and multifaceted, Gene Therapy for HIV and Chronic Infections is an ideal guide for researchers in the fields of gene therapy and immunology interested in expanding their knowledge on how to design an effective gene therapy against a viral pathogen. 000726004 588__ $$aDescription based on online resource; title from PDF title page (viewed March 16 2015). 000726004 650_0 $$aHIV infections$$xGene therapy. 000726004 650_0 $$aHIV infections$$xTreatment. 000726004 7001_ $$aBerkhout, Ben,$$eeditor. 000726004 7001_ $$aErtl, Hildegund C. J.,$$eeditor. 000726004 7001_ $$aWeinberg, Marc S.,$$eeditor. 000726004 77608 $$iPrint version:$$z9781493924318 000726004 830_0 $$aAdvances in experimental medicine and biology ;$$v848. 000726004 852__ $$bebk 000726004 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4939-2432-5$$zOnline Access$$91397441.1 000726004 909CO $$ooai:library.usi.edu:726004$$pGLOBAL_SET 000726004 980__ $$aEBOOK 000726004 980__ $$aBIB 000726004 982__ $$aEbook 000726004 983__ $$aOnline 000726004 994__ $$a92$$bISE