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000726049 020__ $$a9783319121086$$qelectronic book
000726049 020__ $$a3319121081$$qelectronic book
000726049 020__ $$z9783319121079
000726049 0247_ $$a10.1007/978-3-319-12108-6$$2doi
000726049 035__ $$aSP(OCoLC)ocn904962799
000726049 035__ $$aSP(OCoLC)904962799
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000726049 050_4 $$aQP671.C83
000726049 08204 $$a572/.59$$223
000726049 24500 $$aCytochrome P450$$h[electronic resource] :$$bstructure, mechanism, and biochemistry /$$cPaul R. Ortiz de Montellano, editor.
000726049 250__ $$a4th edition.
000726049 264_1 $$aCham :$$bSpringer,$$c2015.
000726049 300__ $$a1 online resource (x, 912 pages) :$$billustrations
000726049 336__ $$atext$$btxt$$2rdacontent
000726049 337__ $$acomputer$$bc$$2rdamedia
000726049 338__ $$aonline resource$$bcr$$2rdacarrier
000726049 500__ $$aIncludes index.
000726049 5050_ $$aVolume 1 -- 1 Structures of Cytochrome P450 Enzymes -- 2 Electron Transfer Partners of Cytochrome P450 -- 3 Activation of Molecular Oxygen in Cytochromes P450 -- 4 Substrate Oxidation by Cytochrome P450 Enzymes -- 5 Inhibition of Cytochrome P450 Enzymes -- 6 Microbial Cytochromes P450 -- 7 P450s in Plants, Insects and their Fungal Pathogens -- 8 P450 Biotechnology -- Volume 2 -- 9 Human Cytochrome P450 Enzymes -- 10 Nuclear Receptor-Mediated Regulation of Cytochrome P450 Genes -- 11 Hormonal Regulation of Liver Cytochrome P450 Enzymes -- 12 P450 Enzymes in Steroid Processing -- 13 P450 Enzymes in Lipid Oxidation.
000726049 506__ $$aAccess limited to authorized users.
000726049 520__ $$aThis authoritative Fourth Edition summarizes the advances of the past decade concerning the structure, mechanism, and biochemistry of cytochrome P450 enzymes, with sufficient coverage of earlier work to make each chapter a comprehensive review of the field. Thirteen chapters are divided into two detailed volumes, the first covering the fundamentals of cytochrome P450 biochemistry, as well as the microbial, plant, and insect systems, and the second exclusively focusing on mammalian systems. Volume 1 begins with an exploration of the biophysics and mechanistic enzymology of cytochrome P450 enzymes, with a discussion of the structures of P450 enzymes and their electron donor partners, the mechanisms of oxygen activation and substrate oxidation, and the approaches and nature of cytochrome P450 inhibition. Two more chapters discuss the nature and roles of cytochrome P450 enzymes in microbes, plants and insects, and an eighth chapter is a survey of the potential utility of P450 enzymes in biotechnology. The first chapter of Volume 2 examines the roles of P450 enzymes in mammals, mainly humans. Four further chapters then deal with the genetic and hormonal regulation of P450 enzymes and their specific roles in the processing of sterols and lipids. Cytochrome P450: Structure, Mechanism, and Biochemistry is a key resource for scientists, professors, and students interested in fields as diverse as biochemistry, chemistry, biophysics, molecular biology, pharmacology and toxicology.
000726049 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 16, 2015).
000726049 650_0 $$aCytochrome P-450.
000726049 650_0 $$aMetalloenzymes.
000726049 7001_ $$aOrtiz de Montellano, Paul R.,$$eeditor.
000726049 77608 $$iPrint version:$$z9783319121079
000726049 852__ $$bebk
000726049 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-12108-6$$zOnline Access$$91397441.1
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000726049 980__ $$aEBOOK
000726049 980__ $$aBIB
000726049 982__ $$aEbook
000726049 983__ $$aOnline
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