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000726074 019__ $$a908097581
000726074 020__ $$a9781489975584$$qelectronic book
000726074 020__ $$a1489975586$$qelectronic book
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000726074 0247_ $$a10.1007/978-1-4899-7558-4$$2doi
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000726074 24500 $$aOral mucosal drug delivery and therapy$$h[electronic resource] /$$cMichael J. Rathbone, Sevda Şenel, Indiran Pather, editors.
000726074 264_1 $$aNew York :$$bSpringer,$$c2015.
000726074 300__ $$a1 online resource (xvi, 279 pages) :$$billustrations.
000726074 336__ $$atext$$btxt$$2rdacontent
000726074 337__ $$acomputer$$bc$$2rdamedia
000726074 338__ $$aonline resource$$bcr$$2rdacarrier
000726074 4901_ $$aAdvances in delivery science and technology,$$x2192-6204
000726074 500__ $$aIncludes index.
000726074 5050_ $$a1 Anatomy and Physiology of the Oral Mucosa -- 2 Design and Development of Oral Mucosal Drug Delivery Systems -- 3 Chemical Methods for Enhancing Oral Mucosal Delivery -- 4 Mucoadhesive Polymers as Enabling Excipients for Oral Mucosal Drug Delivery -- 5 Physical Methods for Enhancing Oral Mucosal Delivery: Sonophoresis, Iontophoresis and Electroporation -- 6 Characterization Methods for Oral Mucosal Drug Delivery -- 7 Design and Development of Systemic Oral Mucosal Drug Delivery Systems -- 8 Tablets and Other Solid Dosage Forms for Systemic Oral Mucosal Drug Delivery -- 9 Formulation of Delivery Systems for Photosensitisers Used in Oral Cavity Photodynamic Therapy -- 10 Medical devices for Oral Mucosal Applications -- 11 Pharmaceuticals for Oral Mucosal Drug Delivery: Regulatory Considerations.
000726074 506__ $$aAccess limited to authorized users.
000726074 520__ $$aThis volume provides a comprehensive overview of the current issues facing scientists working on delivering drugs locally and systemically via the membranes that line the mouth. The book describes the anatomical and physiological challenges of this route for drug delivery and how they impact the design of oral mucosal drug delivery systems. It also provides a detailed description of current oral mucosal drug delivery technologies that overcome these challenges alongside research, development and assessment methods. In 11 authoritative chapters, the book affords an in-depth evaluation of the major issues associated with this route of administration, namely the retention of the drug/product at the site of administration and increasing drug permeability through the oral mucosa. The book provides insights into the in vitro and in vivo methods available to assess drug permeability and retention, offers solutions on how to improve the permeation of the drugs through the oral mucosa, and explores approaches to prolong drug/product retention at the site of administration. It also indicates future directions in research and product development. Oral Mucosal Drug Delivery and Therapy is a key resource for those wishing to extend their knowledge of this field.
000726074 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed March 18, 2015).
000726074 650_0 $$aOral medication.
000726074 650_0 $$aDrug delivery systems.
000726074 7001_ $$aRathbone, Michael J.,$$d1957-$$eeditor.
000726074 7001_ $$aSenel, Sevda,$$eeditor.
000726074 7001_ $$aPather, Indiran,$$eeditor.
000726074 77608 $$iPrint version:$$z9781489975577
000726074 830_0 $$aAdvances in delivery science and technology.
000726074 852__ $$bebk
000726074 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4899-7558-4$$zOnline Access$$91397441.1
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