000726280 000__ 04212cam\a2200529Ii\4500 000726280 001__ 726280 000726280 005__ 20230306140722.0 000726280 006__ m\\\\\o\\d\\\\\\\\ 000726280 007__ cr\cn\nnnunnun 000726280 008__ 150330t20152015gw\\\\\\ob\\\\001\0\eng\d 000726280 020__ $$a9783662463062$$qelectronic book 000726280 020__ $$a3662463067$$qelectronic book 000726280 020__ $$z9783662463055 000726280 0247_ $$a10.1007/978-3-662-46306-2$$2doi 000726280 035__ $$aSP(OCoLC)ocn905854101 000726280 035__ $$aSP(OCoLC)905854101 000726280 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dBTCTA$$dYAM$$dE7B$$dUPM$$dCOO$$dYDXCP$$dIDEBK 000726280 049__ $$aISEA 000726280 050_4 $$aQH445.2 000726280 08204 $$a611.0181663$$223 000726280 24500 $$aGenome mapping and genomics in human and non-human primates$$h[electronic resource] /$$cRavindranath Duggirala, Laura Almasy, Sarah Williams-Blangero, Solomon F.D. Paul, Chittaranjan Kole, editors. 000726280 264_1 $$aHeidelberg :$$bSpringer,$$c[2015] 000726280 264_4 $$c©2015 000726280 300__ $$a1 online resource. 000726280 336__ $$atext$$btxt$$2rdacontent 000726280 337__ $$acomputer$$bc$$2rdamedia 000726280 338__ $$aonline resource$$bcr$$2rdacarrier 000726280 4901_ $$aGenome mapping and genomics in animals ;$$vvolume 5 000726280 504__ $$aIncludes bibliographical references and index. 000726280 5050_ $$aThe Utility of Genomics for Studying Primate Biology -- The Human Genome Project: Where Are We Now and Where Are We Going? -- Linkage Mapping: Localizing the Genes that Shape Human Variation -- Association Studies to Map Genes for Disease-Related Traits in Humans -- Gene Expression Studies and Complex Diseases -- Copy Number Variations and Chronic Diseases -- Applications of Genomic Methods to Studies of Wild Primate Populations -- Comparative Genomics: Tools for Study of Complex Diseases -- Genetic Structure and Its Implications for Genetic Epidemiology: Aleutian Island Populations -- Mapping Genes in Isolated Populations: Lessons from the Old Order Amish -- Genetics of Cardiovascular Disease in Minority Populations -- Mapping of Susceptibility Genes for Obesity, Type 2 Diabetes, and the Metabolic Syndrome in Human Populations -- Genetic Influence on the Human Brain -- Variation, Genetics, and Evolution of the Primate Craniofacial Complex -- Genetic Influences on Behavior in Nonhuman Primates -- Genomic Studies of Human Populations: Re-sequencing Approaches to the Identification of Human Quantitative Loci. 000726280 506__ $$aAccess limited to authorized users. 000726280 520__ $$aThis book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented. Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architecture of normal and disease-related complex phenotypes using data from both humans and non-human primates. 000726280 588__ $$aDescription based on online resource; title from PDF title page (viewed April 1, 2015). 000726280 650_0 $$aHuman gene mapping. 000726280 650_0 $$aPrimates$$xGenome mapping. 000726280 650_0 $$aGenomics. 000726280 7001_ $$aDuggirala, Ravindranath,$$eeditor. 000726280 7001_ $$aAlmasy, Laura,$$eeditor. 000726280 7001_ $$aWilliams-Blangero, Sarah,$$eeditor. 000726280 7001_ $$aPaul, Solomon F.D,$$eeditor. 000726280 7001_ $$aKole, Chittaranjan,$$eeditor. 000726280 77608 $$iPrint version:$$z9783662463055 000726280 830_0 $$aGenome mapping and genomics in animals ;$$vv. 5. 000726280 852__ $$bebk 000726280 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-662-46306-2$$zOnline Access$$91397441.1 000726280 909CO $$ooai:library.usi.edu:726280$$pGLOBAL_SET 000726280 980__ $$aEBOOK 000726280 980__ $$aBIB 000726280 982__ $$aEbook 000726280 983__ $$aOnline 000726280 994__ $$a92$$bISE