000726601 000__ 03858cam\a2200481Ii\4500 000726601 001__ 726601 000726601 005__ 20230306140829.0 000726601 006__ m\\\\\o\\d\\\\\\\\ 000726601 007__ cr\cn\nnnunnun 000726601 008__ 150420s2015\\\\sz\a\\\\ob\\\\000\0\eng\d 000726601 020__ $$a9783319156217$$qelectronic book 000726601 020__ $$a3319156217$$qelectronic book 000726601 020__ $$z9783319156200 000726601 0247_ $$a10.1007/978-3-319-15621-7$$2doi 000726601 035__ $$aSP(OCoLC)ocn907641029 000726601 035__ $$aSP(OCoLC)907641029 000726601 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dGW5XE$$dE7B$$dYDXCP$$dCOO$$dUPM$$dIDEBK$$dEBLCP 000726601 049__ $$aISEA 000726601 050_4 $$aRC392 000726601 08204 $$a616.8/491$$223 000726601 24500 $$aPathophysiology of headaches$$h[electronic resource] :$$bfrom molecule to man /$$cMessoud Ashina, Pierangeo Geppetti, editors. 000726601 264_1 $$aCham :$$bSpringer,$$c[2015] 000726601 300__ $$a1 online resource :$$bcolor illustrations. 000726601 336__ $$atext$$btxt$$2rdacontent 000726601 337__ $$acomputer$$bc$$2rdamedia 000726601 338__ $$aonline resource$$bcr$$2rdacarrier 000726601 4901_ $$aHeadache,$$x2197-6538 ;$$v[2] 000726601 500__ $$a"Endorsed by the European Headache Federation"--Preface. 000726601 504__ $$aIncludes bibliographical references. 000726601 5050_ $$a1 Anatomy of headache -- 2 Animal models of migraine -- 3 Animal models of other primary headaches -- 4 Genetics of headache -- 5 Human models of primary headaches -- 6 Imaging of migraine -- 7 Imaging of other primary headaches -- 8 Neurophysiology of migraine -- 9 Neurophysiology of other primary headaches -- 10 Biochemistry of primary headaches -- 11 Pathophysiology of migraine: current status and future directions -- 12 Pathophysiology of TTH: current status and future directions -- 13 Pathophysiology of cluster headache: current status and future directions -- 14 Pathophysiology of MOH: current status and future directions. 000726601 506__ $$aAccess limited to authorized users. 000726601 520__ $$aThis book provides a detailed overview of the current state of knowledge regarding the pathophysiology of both primary headaches ? migraine, tension-type headache (TTH), and cluster headache ? and the very important and frequent type of secondary headache, medication overuse headache (MOH). After an introductory chapter describing relevant neuroanatomy and vascular anatomy, the evidence gained from animal models regarding the pathophysiology of migraine and the other primary headaches is reviewed. Knowledge of the genetic component in the different types of headache is then examined with reference to recent evidence, for example regarding the implication of the trigeminovascular system and cortical spreading depression in migraine. Detailed information is provided on insights into primary headaches from imaging studies, including functional magnetic resonance imaging and positron emission tomography and on their neurophysiology and biochemistry. A further series of important chapters describe present knowledge of the pathophysiology of each specific type of headache and consider future directions. Written by acknowledged experts in their fields from Europe and the United States, clinicians and students will find Pathophysiology of Headaches to be an excellent source of up-to-date information on why patients experience headaches. In addition, it will be of value for pain researchers investigating the underlying mechanisms of headache. 000726601 588__ $$aOnline resource; title from PDF title page (viewed April 21, 2015). 000726601 650_0 $$aHeadache$$xPathophysiology. 000726601 7001_ $$aAshina, Messoud,$$eeditor 000726601 7001_ $$aGeppetti, Pierangelo,$$eeditor. 000726601 7102_ $$aEuropean Headache Federation. 000726601 77608 $$iPrint version:$$z9783319156200 000726601 830_0 $$aHeadache (Springer (Firm)) ;$$v2. 000726601 852__ $$bebk 000726601 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-15621-7$$zOnline Access$$91397441.1 000726601 909CO $$ooai:library.usi.edu:726601$$pGLOBAL_SET 000726601 980__ $$aEBOOK 000726601 980__ $$aBIB 000726601 982__ $$aEbook 000726601 983__ $$aOnline 000726601 994__ $$a92$$bISE