000726677 000__ 04640cam\a2200493Ii\4500 000726677 001__ 726677 000726677 005__ 20230306140833.0 000726677 006__ m\\\\\o\\d\\\\\\\\ 000726677 007__ cr\cn\nnnunnun 000726677 008__ 150424s2015\\\\sz\a\\\\o\\\\\001\0\eng\d 000726677 020__ $$a9783319136028$$qelectronic book 000726677 020__ $$a331913602X$$qelectronic book 000726677 020__ $$z9783319136011 000726677 0247_ $$a10.1007/978-3-319-13602-8$$2doi 000726677 035__ $$aSP(OCoLC)ocn907948558 000726677 035__ $$aSP(OCoLC)907948558 000726677 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dN$T$$dE7B$$dIDEBK$$dCOO$$dUPM$$dCDX$$dUWO$$dEBLCP 000726677 049__ $$aISEA 000726677 050_4 $$aQP356.47 000726677 08204 $$a616.89$$223 000726677 24500 $$aImmunology and psychiatry$$h[electronic resource] :$$bfrom basic research to therapeutic interventions /$$cNorbert Müller, Aye-Mu Myint, Markus J. Schwarz, editors. 000726677 264_1 $$aCham :$$bSpringer,$$c2015. 000726677 300__ $$a1 online resource (xiv, 408 pages) :$$billustrations. 000726677 336__ $$atext$$btxt$$2rdacontent 000726677 337__ $$acomputer$$bc$$2rdamedia 000726677 338__ $$aonline resource$$bcr$$2rdacarrier 000726677 4901_ $$aCurrent topics in neurotoxicity,$$x2363-9563 000726677 500__ $$aIncludes index. 000726677 504__ $$aIncludes bibliographical references and index. 000726677 5050_ $$aPart I. Basic Science -- 1: Animal models based on immune challenge: the links to brain changes and psychiatric disorders -- 2: The prenatal immune activation model for schizophrenia and the role of stress in puberty -- 3: Rodent models of stress induced depression: the link between stress and immune system related changes -- 4. Experimental Human Endotoxemia, Sickness Behavior and Neuropsychiatric Diseases -- Part II. Translational Medicine -- 5. Mild encephalitis theory of psychiatric disorders -- 6. The role of Infection and autoimmune disorders for schizophrenia and depression: Consequences from a large-scale epidemiological study -- 7. Exposure to microorganisms and adult psychiatric disorders: proofs for causal relationship -- 8. Depression: From activation of immune-inflammatory pathways to oxidative-stress-induced autoimmune responses and neuroprogression -- 9. Immune system related markers changes in childhood neuropsychiatric disorders: cause and consequence -- 10. Cytokines and related metabolic biomarkers in adult neuropsychiatric disorders: possible roles in clinical application -- 11. Immune system changes play a role in the development of the metabolic syndrome in psychiatric disorders -- 12. The activation of microglia in severe neuropsychiatric disorders: Focus on infectious mechanisms and PET imaging -- 13. The role of inflammation in Tourette{u2019}s Syndrome -- 14. The role of inflammation in Autism -- 15. The role of inflammation in Alzheimer{u2019}s Disease -- Part III: Therapeutic application -- 16. Antidepressants: influence on immune system related parameters -- 17. Cyclooxygenase-2 inhibition in management of depression and schizophrenia -- 18. Poly-unsaturated fatty-acids in management of adult psychiatric disorders. 000726677 506__ $$aAccess limited to authorized users. 000726677 520__ $$aPsychiatric disorders are one of the most dramatic burdens for humankind. The role of immune dysfunction in the pathophysiology of these disorders has emerged during the last years, because there has been tremendous progress in psychoneuroimmunological research. Many results are presented here by pioneers in the field. The book addresses various effects of the immune system on the pathophysiology and course of psychiatric disorders and highlights the possible future impact on treatment decisions of various psychiatric disorders, including schizophrenia and depression. The contributions cover the role of in utero immune challenges on the development of schizophrenia, the role of infections, and autoimmune diseases and mild immune activation in the development of depression and schizophrenia, the influence of immune responses in other disorders such as Tourette's, Alzheimer's, and OCD, the connections between mental and physical pain as well as between anti-inflammatory and antipsychotic drugs. 000726677 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed April 24, 2015). 000726677 650_0 $$aNeuroimmunology. 000726677 650_0 $$aMental illness$$xImmunological aspects. 000726677 7001_ $$aMüller, N.$$q(Norbert),$$eeditor. 000726677 7001_ $$aMyint, Aye-Mu,$$eeditor. 000726677 7001_ $$aSchwarz, Markus J.,$$eeditor. 000726677 77608 $$iPrint version:$$z9783319136011 000726677 830_0 $$aCurrent topics in neurotoxicity. 000726677 852__ $$bebk 000726677 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-13602-8$$zOnline Access$$91397441.1 000726677 909CO $$ooai:library.usi.edu:726677$$pGLOBAL_SET 000726677 980__ $$aEBOOK 000726677 980__ $$aBIB 000726677 982__ $$aEbook 000726677 983__ $$aOnline 000726677 994__ $$a92$$bISE