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Part I
1. Introduction: Sleepy days and restless nights of Parkinson's Disease
2. Regulation of sleep and wake homeostasis
3. Neurochemistry of the sleep-wake cycle in Parkinson's disease
4. Impaired sleep and alertness in Parkinson's disease: what did we learn from animal models?
5. Objective measures of the sleep-wake cycle in Parkinson's disease
6. Subjective assessment of sleep and sleepiness in Parkinson's disease. Part II
7. Excessive daytime somnolence associated with Parkinson's disease
8. Insomnia in Parkinson's disease
9. Sleep-disordered breathing in Parkinson's disease
10. Restless legs syndrome and periodic limb movement disorder in Parkinson's disease
11. REM sleep behavior disorder
12. REM sleep behavior disorder: a pre-motor marker of Parkinson's disease
13. Dysregulation of circadian system in Parkinson's disease
14. Cognition and the sleep-wake cycle in Parkinson's disease
15. Fatigue and sleepiness in Parkinson's disease
16. Impact of surgical therapies on sleep and alertness in Parkinson's disease
17. Future directions.

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