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000726929 020__ $$a9783319161044$$qelectronic book
000726929 020__ $$a3319161040$$qelectronic book
000726929 020__ $$z9783319157917
000726929 0247_ $$a10.1007/978-3-319-16104-4$$2doi
000726929 035__ $$aSP(OCoLC)ocn908392100
000726929 035__ $$aSP(OCoLC)908392100
000726929 040__ $$aGW5XE$$beng$$erda$$epn$$cGW5XE$$dYDXCP$$dCOO$$dVLB
000726929 049__ $$aISEA
000726929 050_4 $$aQR171.G29$$bI47 2015eb
000726929 08204 $$a612.3$$223
000726929 24504 $$aThe impact of food bioactives on health$$h[electronic resource] :$$bin vitro and ex vivo models /$$cKitty Verhoeckx, editor-in-Chief ; Paul Cotter [and more], editors.
000726929 264_1 $$aCham :$$bSpringer,$$c2015.
000726929 300__ $$a1 online resource (348 pages) :$$billustrations.
000726929 336__ $$atext$$btxt$$2rdacontent
000726929 337__ $$acomputer$$bc$$2rdamedia
000726929 338__ $$aonline resource$$bcr$$2rdacarrier
000726929 504__ $$aIncludes biblographical references and index.
000726929 5050_ $$aIntroduction -- Gastrointestinal digestion models, general introduction -- Static digestion models general introduction -- InfoGest consensus method -- Approaches to static digestion models -- Dynamic digestion models general introduction -- The TNO gastro-Intestinal Model (TIM) -- Dynamic Gastric Model (DGM) -- Human Gastric Simulator (Riddet model) -- The DIDGI System -- General introduction to cells, cell lines and cell culture -- Epithelial cell models; General introduction -- Caco-2 cell line -- HT29 cell line -- The IPEC-J2 cell line -- Co-cultivation of Caco-2 and HT-29MT -- Innate and adaptive immune cells; General introduction -- THP-1 and U937 cells -- Peripheral blood mononuclear cells -- PBMC-derived T cells -- Dendritic Cells -- Co-culture Caco-2/ immune cells -- Enteroendocrine Cell Models: General introduction -- STC-1 cells -- NCI-H716 cells -- Murine GLUTag cells -- In vitro intestinal tissue models: General introduction -- Intestinal crypt organoids as experimental models -- Porcine ex vivo intestinal segment model -- Ussing chamber -- In vitro fermentation models: General Introduction -- One compartment fermentation model -- The TNO in vitro model of the colon - TIM-2 -- The Simulator of the Human Intestinal Microbial Ecosystem SHIME -- The computer-controlled multicompartmental dynamic model of the gastrointestinal system SIMGI.
000726929 506__ $$aAccess limited to authorized users.
000726929 520__ $$aThis book describes in vitro and ex vivo models that can be employed to investigate effects of digested food products on the GIT, or specific components thereof. Many such models exist and include, for example, those used to study digestion and fermentation in the small and large intestine, to investigate absorption (e.g. Ussing chamber, epithelial cell systems), and to research the immune and enteroendocrine responses (e.g. macrophages, dendritic cells, co-cultures). In each case, these respective assays and models are discussed, and tips and tricks concerning their proper use are given. The Impact of Food Bioactives on Health: In Vitro and Ex Vivo Models is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest. The book highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated, and highlights the strengths and weaknesses of the various assays. It is also an important resource for under-graduate students in the food and health arena.
000726929 588__ $$aDescription based on print version record.
000726929 650_0 $$aGastrointestinal system$$xMicrobiology.
000726929 650_0 $$aDigestion.
000726929 650_0 $$aFood$$xBiotechnology.
000726929 650_0 $$aBioactive compounds.
000726929 7001_ $$aVerhoeckx, Kitty,$$eeditor.
000726929 7001_ $$aCotter, Paul,$$eeditor.
000726929 77608 $$iPrint version:$$tImpact of Food Bioactives on Health$$z3319157914$$w(OCoLC)905486484
000726929 85280 $$bebk$$hSpringerLink
000726929 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-16104-4$$zOnline Access$$91397441.1
000726929 909CO $$ooai:library.usi.edu:726929$$pGLOBAL_SET
000726929 980__ $$aEBOOK
000726929 980__ $$aBIB
000726929 982__ $$aEbook
000726929 983__ $$aOnline
000726929 994__ $$a92$$bISE