000726997 000__ 03109cam\a2200457Ii\4500 000726997 001__ 726997 000726997 005__ 20230306140847.0 000726997 006__ m\\\\\o\\d\\\\\\\\ 000726997 007__ cr\cn\nnnunnun 000726997 008__ 150511s2015\\\\gw\\\\\\ob\\\\000\0\eng\d 000726997 020__ $$a9783642312205$$qelectronic book 000726997 020__ $$a3642312209$$qelectronic book 000726997 020__ $$z9783642312199 000726997 0247_ $$a10.1007/978-3-642-31220-5$$2doi 000726997 035__ $$aSP(OCoLC)ocn908685776 000726997 035__ $$aSP(OCoLC)908685776 000726997 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dN$T$$dOCLCO$$dN$T$$dGW5XE$$dOCLCO$$dYDXCP$$dNUI$$dOCLCA$$dCOO$$dOCLCO$$dEBLCP 000726997 049__ $$aISEA 000726997 050_4 $$aRC280.B8 000726997 08204 $$a616.99449$$223 000726997 24500 $$aBreast cancer biology for the radiation oncologist$$h[electronic resource] /$$cJonathan Strauss, William Small, Gayle E. Woloschak, editors. 000726997 264_1 $$aHeidelberg :$$bSpringer,$$c[2015] 000726997 300__ $$a1 online resource. 000726997 336__ $$atext$$btxt$$2rdacontent 000726997 337__ $$acomputer$$bc$$2rdamedia 000726997 338__ $$aonline resource$$bcr$$2rdacarrier 000726997 4901_ $$aMedical Radiology,$$x0942-5373 000726997 504__ $$aIncludes bibliographical references. 000726997 5050_ $$aBiological subtypes of breast cancer -- Oncogene amplification and Herceptin -- Current clinical use of genetic profiling -- Biology of DCIS and progression to invasive disease -- Cancer Stem Cells and Radiotherapy -- Genetic basis of normal tissue radiosensitivity and late toxicity -- Genetic syndromes and radiotherapy in breast cancer -- Experimental therapies in breast cancer. 000726997 506__ $$aAccess limited to authorized users. 000726997 520__ $$aBreast Cancer Biology for the Radiation Oncologist is the first textbook of its kind devoted to describing the biological complexities of breast cancer in a way that is relevant to the radiation oncologist. Radiation Oncology has long treated breast cancer as a single biological entity, with all treatment decisions being based on clinical and pathologic risk factors. We are now beginning to understand that biological subtypes of breast cancer may have different risks of recurrence as well as different intrinsic sensitivity to radiotherapy. Multi-gene arrays that have for years been used to predict the risk of distant recurrence and the value of systemic chemotherapy may also have utility in predicting the risk of local recurrence. Additionally, the targeted agents used to treat breast cancer may interact with radiotherapy in ways that can be beneficial or undesirable. All of these emerging issues of central importance to radiation oncologists are extensively discussed in this book, and practical treatment recommendations based on available clinical evidence are presented whenever possible. 000726997 650_0 $$aBreast$$xCancer$$xTreatment. 000726997 7001_ $$aStrauss, Jonathan,$$eeditor. 000726997 7001_ $$aSmall, William,$$cJr.,$$eeditor. 000726997 7001_ $$aWoloschak, Gayle E.,$$eeditor. 000726997 77608 $$iPrint version:$$z9783642312199 000726997 830_0 $$aMedical Radiology. 000726997 852__ $$bebk 000726997 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-642-31220-5$$zOnline Access$$91397441.1 000726997 909CO $$ooai:library.usi.edu:726997$$pGLOBAL_SET 000726997 980__ $$aEBOOK 000726997 980__ $$aBIB 000726997 982__ $$aEbook 000726997 983__ $$aOnline 000726997 994__ $$a92$$bISE