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000727179 020__ $$a9783319150635$$qelectronic book
000727179 020__ $$a3319150634$$qelectronic book
000727179 020__ $$z9783319150628
000727179 035__ $$aSP(OCoLC)ocn909367991
000727179 035__ $$aSP(OCoLC)909367991
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000727179 050_4 $$aRC387.5$$b.C45 2015eb
000727179 08204 $$a617.4/81044$$223
000727179 24500 $$aCell therapy for brain injury$$h[electronic resource] /$$cDavid C. Hess, editor.
000727179 264_1 $$aCham :$$bSpringer,$$c[2015]
000727179 264_4 $$c©2015
000727179 300__ $$a1 online resource (xi, 365 pages) :$$billustrations.
000727179 336__ $$atext$$btxt$$2rdacontent
000727179 337__ $$acomputer$$bc$$2rdamedia
000727179 338__ $$aonline resource$$bcr$$2rdacarrier
000727179 504__ $$aIncludes bibliographical references and index.
000727179 5050_ $$aIntroduction to Cell Therapy in Brain Injury -- Cell Based Therapeutics in Stroke: An Industry Perspective -- Autologous Mesenchymal Stem Cell Therapy in Patients with Stroke -- Treatment of Autologous Bone Marrow Mononuclear Cells for Acute and Subacute Stroke: Cell-Therapy for Acute/Subacute Stroke -- Clinical Development of MultiStem® for Treatment of Injuries and Diseases of the Central Nervous System -- Intra-Arterial Approaches to Stem Cell Therapy for Ischemic Stroke -- Neural Stem Cells in Stroke: Intracerebral Approaches -- The CTX Human Neural Stem Cell Line and the PISCES Stroke Trial -- Induced Pluripotent Stem Cells as a Cell-based Therapeutic in Stroke -- Induced Pluripotent Stem Cell Derived Neural Cell Types In Treatment of Stroke -- Preconditioning and Cell-based Therapeutics -- Tracking of Administered Progenitor Cells in Brain Injury and Stroke by Magnetic Resonance Imaging -- Biomaterials Application in Stem Cell Therapies for Stroke -- A Stem Cell Derived Cell-Free Therapy for Stroke: Moving Conditioned Medium into Clinical Trial -- Pathophysiology of Traumatic Brain Injury: Rationale and Role for Cellular Therapies -- Stem Cell Therapy for Neonatal Hypoxic-Ischemic Brain Injury -- Cell-Based Therapies in Neonatal Stroke -- Issues in Clinical Trial Design in Stem Cell Trials after Stroke.
000727179 506__ $$aAccess limited to authorized users.
000727179 520__ $$aThis is a review of state-of-the-art cell therapy in the treatment of stroke, traumatic brain injuries and neonatal stroke and hypoxia-ischemia using a variety of cells ranging from bone marrow derived stem cells and mesenchymal stem cells to induced pluripotent stem cells derived neural progenitors. This invaluable book covers this niche topic in depth from basic stem cell biology and principles of cell therapy through proposed mechanisms of action of cell therapy in stroke, pre-clinical data in stroke models, ongoing clinical trials, imaging and tracking of cells with MRI, neural stem cells in stroke, approaches using conditioned medium, and the "big pharma" perspective of cell therapy. Each of eighteen chapters has been contributed by a well-known leader in each field, thus providing a wealth of international perspective and expertise. Cell Therapy for Brain Injury?s breadth makes it essential reading for neuroscientists, stem cell biologists, researchers or clinical trialists at pharmaceutical or biotechnology companies. It also serves as a thorough introduction for graduate students or post-doctoral fellows who hope to work in these fields.
000727179 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed May 20, 2015).
000727179 650_0 $$aBrain$$xWounds and injuries$$xTreatment.
000727179 650_0 $$aCellular therapy.
000727179 7001_ $$aHess, David C.,$$eeditor.
000727179 852__ $$bebk
000727179 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-15063-5$$zOnline Access$$91397441.1
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000727179 980__ $$aEBOOK
000727179 980__ $$aBIB
000727179 982__ $$aEbook
000727179 983__ $$aOnline
000727179 994__ $$a92$$bISE