@article{727185,
      note = {"Doctoral thesis accepted by the University of Liverpool,  UK."},
      author = {Hatton, Fiona L.,},
      url = {http://library.usi.edu/record/727185},
      title = {Hyperbranched polydendrons a new macromolecular  architecture / [electronic resource] :},
      abstract = {This thesis outlines the first synthesis of a new complex  branched polymer architecture that aims to combine the  benefits of dendrimers with the simplicity of conventional  polymerisation. There is no other available literature on  these remarkable materials, dubbed hyperbranched  polydendrons, due to their novelty. The new materials were  shown to have very high molecular weights (>1,000,000  g/mol), exceptional self-assembly and encapsulation  behaviour and unparalleled functionalisation capabilities,  and were studied pharmacologically to determine their  potential as oral nanomedicine candidates. The detailed  investigation of the chemical variables involved in  synthesising hyperbranched polydendrons has shown that  their self-assembly and pharmacological behaviour can be  turned on and off and fine-tuned by altering the  composition of the materials. The permeation of the  self-assembled particles through model gut epithelium  suggests the potential for oral dosing of drug loaded  nanomedicines that result in circulating nanoparticles ? a  research goal that is currently being pursued by several  groups around the globe.},
      doi = {https://doi.org/10.1007/978-3-319-18753-2},
      recid = {727185},
      pages = {1 online resource (xxii, 260 pages) :},
}