MicroRNA detection and pathological functions [electronic resource] / Xueji Zhang, Haifeng Dong, Yaping Tian.
Zhang, Xueji, author.; Dong, Haifeng, author.; Tian, Yaping, author.
2015
QP623 .Z43 2015eb
Available Online

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Title MicroRNA detection and pathological functions [electronic resource] / Xueji Zhang, Haifeng Dong, Yaping Tian.
Author Zhang, Xueji, author.
ISBN 9783662472934 electronic book
3662472937 electronic book
9783662472927
DOI https://doi.org/10.1007/978-3-662-47293-4
Published Heidelberg : Springer, [2015]
Language English
Description 1 online resource : color illustrations.
Item Number 10.1007/978-3-662-47293-4 doi
Call Number QP623 .Z43 2015eb
Dewey Decimal Classification 572.8/8
Summary This book summarizes microRNA (miRNA) biology in a variety of pathological processes, emphasizing the significant potential applications of miRNA in diagnostics and prognostics, as well as novel drug targets. The conventional techniques used for miRNA detection including standard PCR, Northern blotting, microarray and clone methods are addressed. Recent emerging strategies in miRNA detection and quantification with superior flexibility and adaptability, such as novel molecular biological techniques and locked nucleic acid (LNA) modified probes, as well as nanotechnology-based approaches, are also included. The book also highlights the latest advances in clinical-related miRNA detection methods in living cells, circulating blood and tissue, such as in situ hybridization (ISH) and molecular imaging techniques, which are useful to elucidate the biogenesis and biological function of miRNAs in vivo. Finally, the respective advantages and drawbacks of various detection techniques in this fast-moving field are discussed, along with the challenges and promising new directions. This book offers a valuable resource for analytical chemists, biologists and physicians involved in miRNA research. Dr. Xueji Zhang and Dr. Haifeng Dong are Professors at the School of Chemistry & Biological Engineering, University of Science & Technology Beijing (USTB), China. Dr. Yaping Tian is a Professor at the Department of Clinical Biochemistry, Chinese PLA General Hospital and Military Medical School, China.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (viewed June 1, 2015).
Added Author Dong, Haifeng, author.
Tian, Yaping, author.
Series SpringerBriefs in molecular science.
Available in Other Form Print version: 9783662472927
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Record Appears in Online Resources > Ebooks
All Resources
Introduction
miRNAs Biology in Pathological Processes
Conventional MiRNA Detection Strategies
MiRNA Electrochemical Detection
MiRNA Optical Detection.- Other Emerging MiRNA Detection Strategies
Intracellular and Organic miRNA in Situ Detection
Summary and Prospects.

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