Histone recognition [electronic resource] / Ming-Ming Zhou, editor.
Zhou, Ming-Ming, editor.
2015
QP552.H5 H57 2015eb
Available Online

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Title Histone recognition [electronic resource] / Ming-Ming Zhou, editor.
ISBN 9783319181028 electronic book
3319181025 electronic book
9783319181011
DOI https://doi.org/10.1007/978-319-18102-8
Published Cham : Springer, 2015.
Language English
Description 1 online resource (viii, 282 pages) : illustrations.
Item Number 10.1007/978-319-18102-8 doi
Call Number QP552.H5 H57 2015eb
Dewey Decimal Classification 572/.66
Summary This book provides a timely review of the role of histone modifications in epigenetic control of gene expression. Topics covered include: basic mechanisms of molecular recognition of histone post-translational modification (PTMs); combinatorial readout of histone PTMs by tandem epigenome reader domains; genome-wide profiling of histone PTM interactions; small molecule modulation of histone PTM interactions and their potential as a new approach to therapeutic intervention in human diseases. All chapters were written by leading scientists who made the original key discoveries of the structure and mechanism of evolutionarily conserved reader domains, which serve to direct gene transcription in chromatin through interactions with DNA-packing histones in a PTM-sensitive manner.
Note Includes index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed June 3, 2015).
Added Author Zhou, Ming-Ming, editor.
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Record Appears in Online Resources > Ebooks
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