Metal response in cupriavidus metallidurans. Volume I, From habitats to genes and proteins [electronic resource] / edited by Max Mergeay, Rob Van Houdt.
Mergeay, Max, editor.; Houdt, Rob Van, editor.
2015
QP552.C34 M47 2015eb
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Title Metal response in cupriavidus metallidurans. Volume I, From habitats to genes and proteins [electronic resource] / edited by Max Mergeay, Rob Van Houdt.
ISBN 9783319205946 electronic book
3319205943 electronic book
9783319205939
Published Cham : Springer, 2015.
Language English
Description 1 online resource : color illustrations, color maps
Call Number QP552.C34 M47 2015eb
Dewey Decimal Classification 572/.696
Summary This book is the first volume of a two-volume set summarizing 40 years of key research findings directly related to metal-resistant Cupriavidus/Ralstonia (Betaproteobacteria). In this first volume, the historical and geographical context of these bacteria, which are mostly found in industrial and polluted environments linked to zinc and other non-ferrous metallurgy, is sketched to illustrate the interactions between bacteria and human activities and the possible evolutionary consequences on bacterial genomes especially as far as the association of metal resistance genes with mobile genetic elements is concerned. A detailed description of the response and underlying genetic determinants of type strain Cupriavidus metallidurans CH34 to a variety of metals is provided. With high level resistance to cadmium, chromate, cobalt, copper, mercury, nickel, lead and zinc mediated by well-known genes for detoxification carried by its megaplasmids pMOL28 and pMOL30. This description is complemented with the genomic context of the metal response genes in C. metallidurans CH34 with a focus on its mobilome including insertion sequence elements, transposons, integrative and conjugative elements and genomic islands. In addition, in the second volume, structural and catalytic data from bacterial primary and secondary transporters (P-ATPases, tripartite chemiosmotic cation/proton efflux systems, cation diffusion facilitators, Major Facilitator Superfamily and some minor categories) are outlined and detailed for the corresponding C. metallidurans proteins. The available three-dimensional structures of C. metallidurans proteins are reviewed in detail, including RND and membrane fusion proteins (from tripartite chemiosmotic cation/proton efflux systems), sigma and anti-sigma regulatory proteins of the cnr efflux system (resistance to cobalt and nickel) and various periplasmic proteins mainly involved in the response to copper and mercury.
Bibliography, etc. Note Includes bibliographical references.
Access Note Access limited to authorized users.
Source of Description Online resource; title from title details screen (SpringerLink, viewed July 13, 2015).
Added Author Mergeay, Max, editor.
Houdt, Rob Van, editor.
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The history of Cupriavidus metallidurans strains isolated from anthropogenic environments
Genomic context of metal response genes in Cupriavidus metallidurans with a focus on strain CH34
Response of Cupriavidus metallidurans CH34 to metals.

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