A guide to numerical modelling in systems biology [electronic resource] / Peter Deuflhard, Susanna Röblitz.
Deuflhard, P. (Peter), author.; Röblitz, Susanna, author.
2015
QH323.5
Available Online

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Title A guide to numerical modelling in systems biology [electronic resource] / Peter Deuflhard, Susanna Röblitz.
Author Deuflhard, P. (Peter), author.
ISBN 9783319200590 electronic book
3319200593 electronic book
9783319200583
DOI https://doi.org/10.1007/978-3-319-20059-0
Published Cham : Springer, 2015.
Language English
Description 1 online resource (x, 168 pages) : illustrations.
Item Number 10.1007/978-3-319-20059-0 doi
Call Number QH323.5
Dewey Decimal Classification 570.1/5118
Summary This book is intended for students of computational systems biology with only a limited background in mathematics. Typical books on systems biology merely mention algorithmic approaches, but without offering a deeper understanding. On the other hand, mathematical books are typically unreadable for computational biologists. The authors of the present book have worked hard to fill this gap. The result is not a book on systems biology, but on computational methods in systems biology. This book originated from courses taught by the authors at Freie Universität Berlin. The guiding idea of the courses was to convey those mathematical insights that are indispensable for systems biology, teaching the necessary mathematical prerequisites by means of many illustrative examples and without any theorems. The three chapters cover the mathematical modelling of biochemical and physiological processes, numerical simulation of the dynamics of biological networks, and identification of model parameters by means of comparisons with real data. Throughout the text, the strengths and weaknesses of numerical algorithms with respect to various systems biological issues are discussed. Web addresses for downloading the corresponding software are also included. .
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (SpringerLink, viewed July 17, 2015).
Added Author Röblitz, Susanna, author.
Series Texts in computational science and engineering ; 12.
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Preface
Outline
ODE Models for Systems Biological Networks
Numerical Simulation of ODE Models
Parameter Identification in ODE Models
Appendix
Software
Index.

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