The male role in pregnancy loss and embryo implantation failure [electronic resource] / Richard Bronson, editor.
Bronson, Richard, 1941- editor.
2015
RC889.2
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Title
The male role in pregnancy loss and embryo implantation failure [electronic resource] / Richard Bronson, editor.
ISBN
9783319188812 electronic book
331918881X electronic book
9783319188805
Published
Cham : Springer, 2015.
Copyright
©2015
Language
English
Description
1 online resource.
Call Number
RC889.2
Dewey Decimal Classification
612.6/1
Summary
Novel topics compiled in this one-of-a-kind volume provide tantalizing hints for clinical application through future translational research. Only recently have we come to ask what role the male might play in pregnancy loss and embryo implantation failure, beyond contributing an abnormal set of paternal chromosomes at fertilization. This volume explores the recent evidence that these conditions might also be related to the transmission of previously unrecognized chromosomal micro-deletions and duplications, or via the epigenetic dysregulation of early embryonic gene function by spermatozoal microRNAs or alterations in sperm DNA methylation patterning, or by DNA damage secondary to either reactive oxygen species or environmental toxicants. In addition, the composition of seminal plasma has been found to be highly complex, containing many factors that play important roles in altering the uterine environment and the female immune system permissive of embryo implantation and trophectoderm outgrowth leading to successful pregnancy. Coverage includes an examination of both spermatozoa and seminal fluid component factors.
Bibliography, etc. Note
Includes bibliographical references.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (viewed July 21, 2015).
Added Author
Bronson, Richard, 1941- editor.
Series
Advances in experimental medicine and biology ; v. 868.
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Preface
Meiotic Non-disjunction
Insights into the Origin and Significance of Aneuploidy in Human Spermatozoa
Damage to Sperm DNA Mediated by Reactive Oxygen Species: Its Impact on Human Reproduction and the Health Trajectory of Offspring
Small RNAs: Their Possible Roles in Reproductive Failure
The Sperm Epigenome, Male Aging and Potential Effects on the Embryo
The Role of Uterine NK Cells in Normal Reproduction and Reproductive Disorders
Seminal fluid Signaling in the Female Reproductive Tract: Implications for Reproductive Success and Offspring Health
Role of Seminal Plasma in Human Female Reproductive Failure: Immunomodulation, Inflammation and Infections
Human Leukocyte Antigen-G Within the Male Reproductive System
Implications for Reproduction
Prostasomes
Their Characterization: Implications for Human Reproduction
The Paternal Contribution to Fetal Tolerance
Index.

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