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Table of Contents
1 Clinical forms and animal models of hypophosphatasia
2 Molecular genetics of hypophosphatasia and phenotype-genotype correlations
3 Genetically modified mice for studying TNAP function
4 Tissue-Nonspecific Alkaline Phosphatase in the Developing Brain and in Adult Neurogenesis
5 Rediscovering TNAP in the brain: a major role in regulating the function and development of the cerebral cortex
6 TNAP in the retina
7 Tissue Non-specific Alkaline Phosphatase (TNAP) in vessels of the brain
8 What can we learn about the neural functions of TNAP from studies on other organs and tissues?
9 TNAP, an essential player in membrane lipid rafts of neuronal cells
10 Signal transduction pathways of TNAP: molecular network analyses
11 Vitamin B-6 Metabolism and Interactions with TNAP
12 Tetramisole and levamisole suppress neuronal activity independently from their inhibitory action on Tissue Non-Specific Alkaline Phosphatase in mouse cortex
13 TNAP and Pain Control
14 Neurological symptoms of Hypophosphatasia
15 Recombinant enzyme replacement therapy in hypophosphatasia
16 Neurogenetic Aspects of Hyperphosphatasia in Mabry Syndrome
17 The role of tissue non-specific alkaline phosphatase (TNAP) in Neurodegenerative diseases: Alzheimer's disease in the focus
18 TNAP plays a key role in neural differentiation as well as in neurodegenerative disorders
Index.
2 Molecular genetics of hypophosphatasia and phenotype-genotype correlations
3 Genetically modified mice for studying TNAP function
4 Tissue-Nonspecific Alkaline Phosphatase in the Developing Brain and in Adult Neurogenesis
5 Rediscovering TNAP in the brain: a major role in regulating the function and development of the cerebral cortex
6 TNAP in the retina
7 Tissue Non-specific Alkaline Phosphatase (TNAP) in vessels of the brain
8 What can we learn about the neural functions of TNAP from studies on other organs and tissues?
9 TNAP, an essential player in membrane lipid rafts of neuronal cells
10 Signal transduction pathways of TNAP: molecular network analyses
11 Vitamin B-6 Metabolism and Interactions with TNAP
12 Tetramisole and levamisole suppress neuronal activity independently from their inhibitory action on Tissue Non-Specific Alkaline Phosphatase in mouse cortex
13 TNAP and Pain Control
14 Neurological symptoms of Hypophosphatasia
15 Recombinant enzyme replacement therapy in hypophosphatasia
16 Neurogenetic Aspects of Hyperphosphatasia in Mabry Syndrome
17 The role of tissue non-specific alkaline phosphatase (TNAP) in Neurodegenerative diseases: Alzheimer's disease in the focus
18 TNAP plays a key role in neural differentiation as well as in neurodegenerative disorders
Index.