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000733716 020__ $$a9781493929047$$qelectronic book
000733716 020__ $$a1493929046$$qelectronic book
000733716 020__ $$z9781493929030
000733716 0247_ $$a10.1007/978-1-4939-2904-7$$2doi
000733716 035__ $$aSP(OCoLC)ocn919122980
000733716 035__ $$aSP(OCoLC)919122980
000733716 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dGW5XE$$dN$T$$dIDEBK$$dYDXCP$$dSNK$$dCDX$$dUPM$$dCOO$$dOCLCF
000733716 049__ $$aISEA
000733716 050_4 $$aQH603.C96
000733716 08204 $$a571.6/54$$223
000733716 24504 $$aThe cytoskeleton in health and disease$$h[electronic resource] /$$cHeide Schatten, editor.
000733716 264_1 $$aNew York, NY :$$bSpringer,$$c2015.
000733716 300__ $$a1 online resource (xii, 395 pages) :$$bcolor illustrations
000733716 336__ $$atext$$btxt$$2rdacontent
000733716 337__ $$acomputer$$bc$$2rdamedia
000733716 338__ $$aonline resource$$bcr$$2rdacarrier
000733716 500__ $$aIncludes index.
000733716 5050_ $$aPart 1. Overview of the Cytoskeleton -- Brief Overview of the Cytoskeleton -- Part 2. Focus on Cytoskeletal Interactions -- Cytoskeleton Dynamics in Health and Disease: Role of Molecular Switches and Rheostats -- Regulation of Cytoskeleton by the Rho Family of GTPases in Hematopoietic Stem Cells in Health and Disease -- The Role of the Cytoskeleton in Cell Migration, Its Influence on Stem Cells and the Special Role of GFAP in Glial Functions -- Centrosome-Microtubule Interactions in Health, Disease, and Disorders -- Cytoskeletal Elements and Reproductive Success in Animals -- Part 3. Focus on Microtubules -- Cytoskeleton and Regulation of Mitochondrial Translocation in Mammalian Eggs -- Tubulin Detyrosination in Epithelial Cells -- Mutations in Adenomatous Polyposis Coli, Their Role in Cytoskeletal Dynamics and Cancer Onset -- Small GTPases Act as Cellular Switches in the Context of Cilia -- Part 4. Focus on Intermediate Filaments -- Desmin Plays Dual Structural and Regulatory Functions Through Its Interaction with Partners in Muscle -- Desmin Filaments and Desmin-Related Myopathy -- Possible Functions of Intermediate Filaments in Mammalian Ovarian Follicles and Oocytes -- Part 5. Focus on Microfilaments -- Actin Organizing Proteins in Regulation of Osteoclast Function -- The Role of Drebrin-Binding Stable Actin Filaments in Dendritic Spine Morphogenesis -- The Role of the Actin Cytoskeleton in Cancer and Its Potential Use as a Therapeutic Target.
000733716 506__ $$aAccess limited to authorized users.
000733716 520__ $$aThis volume℗ℓexplores the cytoskeleton, examining its structural and functional roles and its dysfunctions which often lead to disease.℗ℓMicrotubules, microfilaments, intermediate filaments, and cytoskeletal functions and dysfunctions in different organ systems are thoroughly discussed. The text is organized into four sections, each of which covers℗ℓspecific subtopics. These consist of℗ℓan introductory chapter℗ℓfollowed by topics of current interest and expert-provided contributions which℗ℓinclude each topic's℗ℓkey cell and molecular details. Comprehensive℗ℓyet concise,℗ℓ℗ℓThe Cytoskeleton in Health and Disease℗ℓpresents cutting- edge new℗ℓknowledge℗ℓbalanced with background information, both of which are readily understandable for the newcomer and for the experienced researcher alike. The book℗ℓhighlights the new aspects of the℗ℓresearch and its impact on℗ℓ the design of℗ℓnew strategies or the identification of new targets for therapeutic intervention. This book will be essential reading for scientists, students, teachers who are interested in expanding their knowledge related to the cytoskeleton for diagnostic, therapeutic or℗ℓresearch-based purposes.
000733716 588__ $$aOnline resource; title from PDF title page (viewed August 26, 2015)
000733716 650_0 $$aCytoskeleton.
000733716 7001_ $$aSchatten, Heide,$$eeditor.
000733716 77608 $$iPrint version:$$z9781493929030
000733716 852__ $$bebk
000733716 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4939-2904-7$$zOnline Access$$91397441.1
000733716 909CO $$ooai:library.usi.edu:733716$$pGLOBAL_SET
000733716 980__ $$aEBOOK
000733716 980__ $$aBIB
000733716 982__ $$aEbook
000733716 983__ $$aOnline
000733716 994__ $$a92$$bISE