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000733748 020__ $$a9783319186030$$qelectronic book
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000733748 0247_ $$a10.1007/978-3-319-18603-0$$2doi
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000733748 24500 $$aImmune responses to biosurfaces$$h[electronic resource] :$$bmechanisms and therapeutic interventions /$$cJohn D. Lambris, Kristina N. Ekdahl, Daniel Ricklin, Bo Nilsson, editors.
000733748 264_1 $$aCham :$$bSpringer,$$c2015.
000733748 300__ $$a1 online resource.
000733748 336__ $$atext$$btxt$$2rdacontent
000733748 337__ $$acomputer$$bc$$2rdamedia
000733748 338__ $$aonline resource$$bcr$$2rdacarrier
000733748 4901_ $$aAdvances in experimental medicine and biology ;$$v865
000733748 500__ $$aIncludes index.
000733748 5050_ $$aPart 1. Mechanisms -- Thromboinflammation in Therapeutic Medicine -- Complement Interactions with Blood Cells, Endothelial Cells and Microvesicles in Thrombotic and Inflammatory Conditions -- Role of Complement on Broken Surfaces after Trauma -- Complement Involvement in Periodontitis: Molecular Mechanisms and Rational Therapeutic Approaches -- Part 2. Biomaterials -- The Lectin Pathway of Complement and Biocompatibility -- Foreign Body Reaction to Subcutaneous Implants -- Molecular Characterization of Macrophage-Biomaterial Interactions -- Heparan Sulfate Proteoglycan Metabolism and the Fate of Grafted Tissues -- Part 3. Transplantation -- Xenotransplantation of Cells, Tissues, Organs and the German Research Foundation Transregio Collaborative Research Centre 127 -- Macro encapsulated Pig Islets Correct Induced Diabetes in Primates up to 6 Months -- Regulation of Instant Blood Mediated Inflammatory Reaction (IBMIR) in Pancreatic Islet Xeno-Transplantation?Points for Therapeutic Interventions -- Cell Surface Engineering for Regulation of Immune Reactions in Cell Therapy -- Complement Interception Across Humoral Incompatibility in Solid Organ Transplantation?A Clinical Perspective.
000733748 506__ $$aAccess limited to authorized users.
000733748 520__ $$aThe collection of chapters in this proceedings volume brings together research from academic and industry scientists and clinical development experts who are focused on contemporary and emerging aspects of improving treatments employing biosurfaces. Interactions between biomaterial implants, devices, cell therapies, and whole organ transplants frequently trigger activation of body defense systems and responses that negatively affect the clinical outcome. Optimal tissue integration and modulation of foreign body reactions is therefore essential for preserving anticipated functions and avoiding adverse effects. Topics covered include mechanistic and applied research within the fields of extracorporeal devices, soft and hard tissue implants, tissue and biomaterial-targeting, therapeutic modulation of foreign body reactions, cell encapsulations, as well as cell and whole organ transplantation.
000733748 588__ $$aOnline resource; title from PDF title page (SpringerLink, viewed September 1, 2015).
000733748 650_0 $$aBiological interfaces$$vCongresses.
000733748 650_0 $$aImmune response$$xMolecular aspects$$vCongresses.
000733748 7001_ $$aLambris, J. D.$$q(John D.),$$eeditor.
000733748 7001_ $$aEkdahl, Kristina N.,$$eeditor.
000733748 7001_ $$aRicklin, Daniel,$$eeditor.
000733748 7001_ $$aNilsson, Bo,$$eeditor.
000733748 7112_ $$aInternational Conference on Immune Response to Biosurfaces$$n(1st :$$d2014 :$$cChania, Greece)
000733748 77608 $$iPrint version:$$z9783319186023
000733748 830_0 $$aAdvances in experimental medicine and biology ;$$v865.
000733748 852__ $$bebk
000733748 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-18603-0$$zOnline Access$$91397441.1
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000733748 983__ $$aOnline
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