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Title
The vertebrate blood-gas barrier in health and disease [electronic resource] : structure, development and remodeling / Andrew N. Makanya, editor.
ISBN
9783319183923 electronic book
3319183923 electronic book
9783319183916
Published
Cham : Springer, 2015.
Language
English
Description
1 online resource (xiv, 243 pages) : color illustrations
Item Number
10.1007/978-3-319-18392-3 doi
Call Number
QP99.3.G3
Dewey Decimal Classification
573.1/5
Summary
This comprehensive volume on the blood-gas barrier (BGB) among vertebrates covers its structure and composition along with aspects of evolution, bioengineering, and morphometry. The book also discusses the embryological development of the BGB, including chronology of events and molecular control in vertebrates; modulation of the barrier function, including cyclic stretch-induced increases in alveolar epithelial permeability; mechanisms of lung vascular/epithelial permeability; transport mechanisms of the BGB, including sodium transport channels; factors affecting trans-barrier traffic of fluids, such as chronic elevation of pulmonary microvascular pressure; stress failure; regulation and repair in acute lung injury; chronic lung disease; and lung transportation. Ten authoritative chapters approach the blood-gas barrier holistically, from basic structure and development to pathology and treatment. Properties of the ℗ℓBGB are discussed in the earlier chapters, followed by prenatal and post-natal development and mechanisms of the healthy BGB. The latter half of the book delves into the pathology of the ℗ℓBGB, analyzing common afflictions and exploring options for treatment, including its alterations during lung transplantation. Intuitively structured and comprehensive, The Vertebrate Blood-Gas Barrier in Health and Disease is ideal for researchers and clinicians interested in pneumology and angiology.
Bibliography, etc. Note
Includes bibliographical references and index.
Access Note
Access limited to authorized users.
Source of Description
Online resource; title from PDF title page (SpringerLink, viewed September 1, 2015).
Available in Other Form
Print version: 9783319183916
Chapter 1 Generalities of gas diffusion applied to the vertebrate blood-gas barriers
Chapter 2 Morphological and morphometric properties of the blood-gas barrier: comparative perspectives
Chapter 3 Prenatal and postnatal development of the vertebrate blood-gas barrier
Chapter 4 Molecular mechanisms regulating the pulmonary blood-gas barrier (BGB)
Chapter 5 Barrier enhancing signals
Chapter 6 Trans-barrier ion and fluid transport
Chapter 7 Stress failure of the pulmonary blood-gas barrier
Chapter 8 The lung endothelial barrier in acute inflammation
Chapter 9 Lung transplantation and the blood-gas-barrier
Chapter 10 Stereological studies on transient gas-exchangers, with emphasis on the structure and function of the human placenta in normal and compromised pregnancies.
