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000734953 010__ $$z  2011499097
000734953 020__ $$z9781849730136$$qhardcover
000734953 020__ $$z184973013X$$qhardcover
000734953 020__ $$a9781849731096$$qelectronic book
000734953 035__ $$a(CaPaEBR)ebr10627687
000734953 035__ $$a(OCoLC)776987438
000734953 040__ $$aCaPaEBR$$cCaPaEBR
000734953 05014 $$aQD79.C454$$bT48 2010eb
000734953 08204 $$a543.84$$222
000734953 1001_ $$aTeutenberg, Thorsten.
000734953 24510 $$aHigh-temperature liquid chromatography$$h[electronic resource] :$$ba user's guide for method development /$$cThorsten Teutenberg.
000734953 260__ $$aCambridge :$$bRSC Pub.,$$cc2010.
000734953 300__ $$ax, 210 p. :$$bill.
000734953 440_0 $$aRSC chromatography monographs,$$x1757-7055 ;$$v13
000734953 504__ $$aIncludes bibliographical references and index.
000734953 5050_ $$aA brief definition of high-temperature liquid chromatography -- System set-up for high-temperature liquid chromatography -- The heating system -- Mobile phase considerations -- Suitable stationary phases -- Method development using temperature as an active variable -- Analyte stability -- Special hyphenation techniques -- Critical outlook and future prospects.
000734953 506__ $$aAccess limited to authorized users.
000734953 520__ $$a"High-temperature liquid chromatography has attracted much interest in recent years but has not yet recognized its full potential in the chromatographic community. There is a widespread reluctance in industry to use temperature to speed up the separation process, influence the selectivity of a separation or implement novel detection techniques. However, the technology has now matured and could revolutionize chromatography as we see it today. Better equipment, such as heating systems able to generate faster heating rates, is becoming more readily available. Also, columns based on silica gel, which can withstand higher temperatures for an extended period, are now being introduced. Nevertheless, further technological and methodical efforts are needed to establish the method in a regulated environment like the pharmaceutical industry. This is the only text to cover all the practical aspects, as well as the underlying theoretical principles, of setting up an HPLC system for high temperature operation. It is not intended solely for academics but will also benefit the researcher interested in more practical considerations. The author is a recognized expert and has conducted several studies with partners from industry to validate the method. Many real examples from these studies have been included in the book. The aim is to support practitioners in the creation of their own protocols without the need to rely solely on trial and error. The book starts with a brief definition of high temperature liquid chromatography before going on to cover: system set up; the heating system; mobile phase considerations; suitable stationary phases; method development using temperature programming; analyte stability, and special hyphenation techniques using superheated water as a mobile phase. In each chapter, experimental data is used to illustrate the main statements and the advantages over conventional HPLC are evaluated. The book concludes with a critical outlook on further developments and applications underlining the necessary advances needed to make high temperature HPLC more robust."--Back cover.
000734953 650_0 $$aHigh performance liquid chromatography.
000734953 650_0 $$aHigh temperature chemistry.
000734953 852__ $$bebk
000734953 85640 $$3ProQuest Ebook Central Academic Complete$$uhttps://univsouthin.idm.oclc.org/login?url=http://site.ebrary.com/lib/usiricelib/Doc?id=10627687$$zOnline Access
000734953 909CO $$ooai:library.usi.edu:734953$$pGLOBAL_SET
000734953 980__ $$aEBOOK
000734953 980__ $$aBIB
000734953 982__ $$aEbook
000734953 983__ $$aOnline