Cancer stem cells [electronic resource] : emerging concepts and future perspectives in translational oncology / Sadegh Babashah.
Babashah, Sadegh, editor.
2015
RC269.7
Available Online

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Title Cancer stem cells [electronic resource] : emerging concepts and future perspectives in translational oncology / Sadegh Babashah.
ISBN 9783319210308 electronic book
3319210300 electronic book
9783319210292
Published Cham : Springer, 2015.
Language English
Description 1 online resource
Call Number RC269.7
Dewey Decimal Classification 616.99/402774
Summary The concept of cancer stem cells has great clinical implications. This is due to the fact that small subpopulations of these cells have been identified in a variety of neoplastic conditions ranging from solid tumors to liquid malignancies. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis. This has represented the potential of cancer stem cells in the development of novel and innovative tools for the treatment of metastatic tumors. This book aims to offer a broad framework for obtaining insight into the state-of-the-art knowledge on cancer stem cell biology and highlight the therapeutic implications of these cells in the future of clinical oncology.
Bibliography, etc. Note Includes bibliographical references and index.
Access Note Access limited to authorized users.
Source of Description Online resource; title from PDF title page (viewed November 18, 2015)
Added Author Babashah, Sadegh, editor.
Linked Resources Online Access
Record Appears in Online Resources > Ebooks
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Preface
I. The Biology of Cancer Stem Cells
Cancer Stem Cells: A Quick Walk through the Concepts
Cytokine Networks and Cancer Stem Cells
Implications of CXCR4/CXCL12 Interaction for Cancer Stem Cell Maintenance and Cancer Progression
Non-coding RNAs in Cancer and Cancer Stem Cells. Self-renewal Pathways in Mammary Stem Cells and Carcinogenesis II. Cancer Stem Cells in Human Malignancies
Breast Cancer Stem Cells
Lung Cancer Stem Cells
Colorectal Cancer Stem Cells
Pancreatic Cancer Stem Cells
Glioblastoma Cancer Stem Cells
Head and Neck Cancer Stem
Leukemic and Lymphoid Stem Cells
Leukemic Stem Cells in Acute Lymphoblastic Leukemia
III. Novel Approaches for Targeting Cancer Stem Cells
Targeting Key Stemness-Related Pathways in Human Cancers
Targeting Cancer Stem Cells and the Tumor Microenvironment
Cancer Stem Cells and Chemoresistance: Strategies to Overcome Therapeutic Resistance
Cancer Stem Cells and Tumor Radioresistance
Therapeutic Implications of Cancer Stem Cell: Challenges and Opportunities in Translational Studies. Index.

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