The development of immunologic competence [electronic resource] / Domenico Ribatti.
2015
QR181
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Can lend chapters, not whole ebooks
Details
Title
The development of immunologic competence [electronic resource] / Domenico Ribatti.
ISBN
9783319246635 electronic book
3319246631 electronic book
9783319246611
3319246615
3319246631 electronic book
9783319246611
3319246615
Published
Cham : Springer International Publishing, [2015]
Copyright
©2015
Language
English
Description
1 online resource (viii, 60 pages) : color illustrations, photographs
Item Number
10.1007/978-3-319-24663-5 doi
Call Number
QR181
Dewey Decimal Classification
616.079
Summary
This book traces significant aspects of the history of immunology, exploring the immune system and immunodeficiency. The author recounts human hematopoietic development, and how a distinction of the immune system into thymus-dependent and thymus-independent components has been demonstrated in different animal species, including amphibians, birds, and mammals. Other themes explored in this book include discoveries about the role of the thymus of the Bursa of Fabricius in the development of immunologic competence, and observations on the changes in the lymphoid organs after bursectomy and thymectomy in chickens. Readers will discover how the bursa provides a unique microenvironment for the proliferation and differentiation of B cells, while thymectomized and irradiated animals were deficient in lymphocytes that mediated inflammatory responses, as assessed by skin graft rejection, delayed-type hypersensitivity, and graft versus host reaction. A clear perspective for understanding several diseases and also the entire lymphoid system emerges through the experiments and extensive histopathological studies of patients with primary immunodeficiency diseases that are described in these chapters. Researchers in the life sciences, in biomedicine and the history of medicine will all find something of value in this highly engaging work. It will also appeal to those with an interest in public health and neurobiology.
Bibliography, etc. Note
Includes bibliographical references (pages 47-57) and index.
Access Note
Access limited to authorized users.
Digital File Characteristics
text file PDF
Source of Description
Online resource; title from PDF title page (viewed December 15, 2015).
Available in Other Form
The Development of Immunologic Competence
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Table of Contents
Preface.- Introduction.- Human hematopoietic development.-The Bursa of Fabricius.- The Thymus.- Clinical correlates
References
Index. .
References
Index. .