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000737568 019__ $$a930836429$$a931593323
000737568 020__ $$a9783319248448$$qelectronic book
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000737568 1001_ $$aFleenor, Bradley S.,$$eauthor.
000737568 24510 $$aArterial stiffness$$h[electronic resource] :$$bimplications and interventions /$$cBradley S. Fleenor, Adam J. Berrones.
000737568 264_1 $$aCham :$$bSpringer,$$c[2015]
000737568 264_4 $$c©2015
000737568 300__ $$a1 online resource :$$billustrations.
000737568 336__ $$atext$$btxt$$2rdacontent
000737568 337__ $$acomputer$$bc$$2rdamedia
000737568 338__ $$aonline resource$$bcr$$2rdacarrier
000737568 4901_ $$aSpringerBriefs in physiology
000737568 504__ $$aIncludes bibliographical references and index.
000737568 5050_ $$aPreface; Contents; Chapter 1: Overview of Arterial Stiffness; What Is Arterial Stiffness?; Pathophysiology of Arterial Stiffness; Aortic Function and Physiology; Implications Throughout the Arterial Tree; Large Elastic Arteries; Muscular (Small and Medium) Arteries and Arterioles; Aspects of Arterial Stiffness; Functional Changes; Structural Changes; Assessing Arterial Stiffness in Adults; Pulse Wave Velocity; Pulse Wave Analysis to Assess Central Hemodynamic Parameters; Central Pulse Pressure; Augmentation Index (AIx); Intima-Media Thickness (IMT)
000737568 5058_ $$aPathophysiological Role of Arterial Stiffness in CVDIncrease in SBP, Central Pulse Pressure and Left Ventricle Afterload; Decrease in Coronary Perfusion Pressure; Summary; References; Chapter 2: Mechanisms of Arterial Stiffness; Introduction; Functional Changes Contributing to Arterial Stiffness; Blood Pressure; Impaired Smooth Muscle Function; Impaired Endothelium-Dependent Dilation; Structural Changes Contributing to Arterial Stiffness; Gross Morphological Changes; Compositional Changes; Collagen; Elastin; Advanced Glycation End-Products (AGEs); Calcium; Cellular Changes
000737568 5058_ $$aSignaling MechanismsOxidative Stress; Inflammation; Nitric Oxide (NO); Transforming Growth Factor Beta 1 (TGF-β1); Advanced Glycation End-Products (AGEs); Summary; References; Chapter 3: Implications of Arterial Stiffness; Arterial Stiffness as a Cardiovascular Disease (CVD) Biomarker; Epidemiology; Aging; Sex; Race; Body Composition; Habitual Exercise Training; Cardiorespiratory Fitness; Strength Training; Target Organ Damage; The Heart; The Brain; The Kidneys; Summary; References; Chapter 4: Interventions to Destiffen Arteries; Arterial Stiffness Overview
000737568 5058_ $$aNutraceuticals and Functional FoodsPolyphenolic Compounds; Flavonoids; Isoflavones; Pigments (Anthocyanins and Betalains); Omega-3 Fatty Acids; Micronutrients; Sodium Restriction; Antioxidant Vitamins (C and E); Chronic Exercise Training; Lifestyle Modifications; Weight Loss; Summary; References; Index
000737568 506__ $$aAccess limited to authorized users.
000737568 520__ $$aArterial stiffness is an emerging risk factor with important implications for cardiovascular disease risk. Herein, we concisely summarize the physiological and pathophysiological aspects of arterial stiffening, and highlight the importance of increased arterial stiffness for future cardiovascular events. Factors contributing to increased arterial stiffness such as advancing age, obesity, race, sex differences and cardiorespiratory fitness are examined while elucidating the potential underlying mechanisms for each scenario. To conclude, we discuss novel interventions to prevent and/or reverse the arterial stiffening process in order to reduce cardiovascular risk. This book also: Overviews the cellular and molecular mechanisms of arterial stiffness Discusses the implications of arterial stiffness in target organ damage.
000737568 588__ $$aOnline resource ; title from PDF title page (viewed December 10, 2015).
000737568 650_0 $$aArteriosclerosis.
000737568 7001_ $$aBerrones, Adam J.,$$eauthor.
000737568 77608 $$iPrint version:$$aFleenor, Bradley S.$$tArterial Stiffness : Implications and Interventions$$dCham : Springer International Publishing,c2015$$z9783319248424
000737568 830_0 $$aSpringerBriefs in physiology.
000737568 85280 $$bebk$$hSpringerLink
000737568 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-24844-8$$zOnline Access$$91397441.1
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000737568 982__ $$aEbook
000737568 983__ $$aOnline
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