000737569 000__ 03697cam\a2200457Ii\4500
000737569 001__ 737569
000737569 005__ 20230306141047.0
000737569 006__ m\\\\\o\\d\\\\\\\\
000737569 007__ cr\cn\nnnunnun
000737569 008__ 151201s2015\\\\ja\\\\\\ob\\\\001\0\eng\d
000737569 019__ $$a930836934$$a931593276
000737569 020__ $$a9784431557630$$qelectronic book
000737569 020__ $$a4431557636$$qelectronic book
000737569 020__ $$z9784431557623
000737569 020__ $$z4431557628
000737569 035__ $$aSP(OCoLC)ocn930703283
000737569 035__ $$aSP(OCoLC)930703283$$z(OCoLC)930836934$$z(OCoLC)931593276
000737569 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dIDEBK$$dEBLCP$$dYDXCP$$dN$T$$dOCLCO$$dAZU
000737569 049__ $$aISEA
000737569 050_4 $$aQP86
000737569 08204 $$a612.67$$223
000737569 24500 $$aAging mechanisms$$h[electronic resource] :$$blongevity, metabolism, and brain aging /$$cNozomu Mori, Inhee Mook-Jung, editors.
000737569 264_1 $$aTokyo :$$bSpringer,$$c2015.
000737569 300__ $$a1 online resource.
000737569 336__ $$atext$$btxt$$2rdacontent
000737569 337__ $$acomputer$$bc$$2rdamedia
000737569 338__ $$aonline resource$$bcr$$2rdacarrier
000737569 504__ $$aIncludes bibliographical references and idnex.
000737569 5050_ $$aPreface -- Part I From Hypotheses to Mechanisms -- Part II Human Longevity: Centenarianism and Progeria -- Part III Stem Cells, Cultured Neurons, and Lower Animal Models -- Part IV Metabolism: Factors Affecting Tissue Aging -- Part V Aging Brain: Adult Neurogenesis, Synaptic Plasticity, and Brain Volume -- Part VI Aged Brain: Mechanisms of Neurodegeneration -- Part VII Anti-Brain Aging: Neuroprotection and Therapeutic Approaches -- Epilogue -- Appendix -- Index. .
000737569 506__ $$aAccess limited to authorized users.
000737569 520__ $$aThis book brings together the most up-to-date information on recent research results of leading laboratories on aging science in East Asia, particularly in Japan, Korea, and Hong Kong. Starting with a comprehensive overview of various hypotheses on biological mechanisms of aging by Dr. Sataro Goto, each chapter covers broad aspects of the most recent findings in aging-related topics: centenarian studies and genome analysis of progeria, metabolic biochemistry and neurobiology, longevity controls in yeast and nematodes, oxidative stress and calorie restriction, and neurodegeneration mechanisms in Alzheimer's and Huntington's diseases, with further potential therapeutic approaches to these age-related neurodegenerative diseases. Also included, in part, is a summary and the outcomes of a scientific discussion forum called the Asian Aging Core for Longevity (AACL) that has been held annually alternating between Japan and Korea during the last decade. This book can serve as a useful resource for finding appropriate collaborators in the areas it covers. The target readership is made up of graduate students and researchers at universities, medical and/or life-science schools, and biomedical and pharmaceutical institutes. Why does aging exist? How do we age? How is each organism's lifespan determined? These are fundamental questions in the field. We may be still far from achieving a complete view of aging mechanisms, but this book, Aging Mechanisms, offers an excellent opportunity to become familiar with the most updated progress in the biomedical research of aging in Japan and Korea, the two leading nations for human longevity.
000737569 588__ $$aOnline resource; title from PDF title page (viewed December 16, 2015)
000737569 650_0 $$aAging$$xPhysiological aspects.
000737569 650_0 $$aLongevity.
000737569 650_0 $$aAging.
000737569 7001_ $$aMori, Nozomu,$$eeditor.
000737569 7001_ $$aMook-Jung, Inhee,$$eeditor.
000737569 85280 $$bebk$$hSpringerLink
000737569 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-4-431-55763-0$$zOnline Access$$91397441.1
000737569 909CO $$ooai:library.usi.edu:737569$$pGLOBAL_SET
000737569 980__ $$aEBOOK
000737569 980__ $$aBIB
000737569 982__ $$aEbook
000737569 983__ $$aOnline
000737569 994__ $$a92$$bISE