000737586 000__ 03969cam\a2200457Ii\4500 000737586 001__ 737586 000737586 005__ 20230306141048.0 000737586 006__ m\\\\\o\\d\\\\\\\\ 000737586 007__ cr\cn\nnnunnun 000737586 008__ 151201s2015\\\\sz\a\\\\o\\\\\100\0\eng\d 000737586 019__ $$a931593262 000737586 020__ $$a9783319234977$$qelectronic book 000737586 020__ $$a3319234978$$qelectronic book 000737586 020__ $$z9783319234960 000737586 035__ $$aSP(OCoLC)ocn930703361 000737586 035__ $$aSP(OCoLC)930703361$$z(OCoLC)931593262 000737586 040__ $$aN$T$$beng$$erda$$epn$$cN$T$$dYDXCP$$dIDEBK$$dEBLCP$$dOCLCO$$dN$T$$dOCLCO 000737586 049__ $$aISEA 000737586 050_4 $$aQA1-939 000737586 08204 $$a510 000737586 1001_ $$aZazzu, Valeria,$$eeditor. 000737586 24510 $$aMathematical models in biology$$h[electronic resource] :$$bbringing mathematics to life /$$cValeria Zazzu, Maria Brigida Ferraro, Mario R. Guarracino, editors. 000737586 264_1 $$aCham :$$bSpringer,$$c2015. 000737586 300__ $$a1 online resource (xii, 199 pages) :$$billustrations. 000737586 336__ $$atext$$btxt$$2rdacontent 000737586 337__ $$acomputer$$bc$$2rdamedia 000737586 338__ $$aonline resource$$bcr$$2rdacarrier 000737586 5050_ $$aPreface; Acknowledgments; Contents; Image Segmentation, Processing and Analysis in Microscopy and Life Science; 1 Pixels and Color Channels; 2 Image Segmentation; 2.1 Thresholding; 2.2 Watershed Segmentation; 2.3 Shape-Based Watershed Segmentation; 2.4 Edge-Based Watershed Segmentation; 2.5 Merging; 2.6 Seeded Watershed Segmentation; 2.7 Extension to Volume Images and Time-Lapse Experiments; 2.8 Other Segmentation Methods; 3 Feature Extraction and Classification in Large-Scale Image Based Biomedical Screening; References 000737586 5058_ $$aImage Analysis and Classification for High-Throughput Screening of Embryonic Stem Cells1 Introduction; 2 Software System Components; 2.1 Pre-Processing; 2.2 Segmentation; 2.3 Features Computation; 2.4 Classification; 3 Experimental Results; 3.1 Performance Metrics; 3.2 Evaluation of the Segmentation Step; 3.3 First Classification Results; 4 Concluding Remarks; References; Exploiting ``Mental'' Images in Artificial NeuralNetwork Computation; 1 Introduction; 2 DRASiW Model; 3 Mental Images; 4 Improving DRASiW Performance; 4.1 Tracking Deformable Objects; 4.2 Generating Background Models 000737586 5058_ $$a4.3 Improving Classification5 Conclusions; References; Applying Design of Experiments Methodology to PEI Toxicity Assay on Neural Progenitor Cells; 1 Design of Experiments as a Method for Protocol Optimization; 2 Main Aspects of DoE Methodology; 3 DoE Applications from Industry to Biological Research; 4 Our Case Study: The Set-Up and Optimisation of a Transfection Protocol for Neural Progenitor Cells; 5 DoE Methodology Applied to Toxicity Assay; 5.1 Factorial Designs and Residual Analysis; 5.2 Factors and Interactions Significance Analysis; 5.3 Model Refining and Validation; 6 Conclusions 000737586 5058_ $$a2 MiRNA Transcriptional Regulation2.1 Challenges of in silico miRNA Promoter Identification; 2.2 Next Generation Sequencing (NGS) Technology Leads to Significant Advances in miRNA Promoter Prediction; 2.3 Classification and Comparison of miRNA Promoter Prediction Methods; 2.3.1 miRNA-Mediated Regulatory Network Reconstruction; 3 Predictive Models of miRNA Processing; 4 Conclusions; References; Tunicate Neurogenesis: The Case of the SoxB2 Missing CNE; 1 Introduction; 2 Results; 3 Discussion; 4 Materials and Methods; 4.1 Animals and Embryos; 4.2 Comparative Genomics 000737586 506__ $$aAccess limited to authorized users. 000737586 650_0 $$aBiology$$xMathematical models$$vCongresses. 000737586 650_0 $$aBiometry$$vCongresses. 000737586 7001_ $$aFerraro, Maria Brigida,$$eeditor. 000737586 7001_ $$aGuarracino, Mario R.,$$eeditor. 000737586 77608 $$iPrint version:$$tMathematical Models in Biology : Bringing Mathematics to Life$$dCham : Springer International Publishing,c2015$$z9783319234960 000737586 85280 $$bebk$$hSpringerLink 000737586 85640 $$3SpringerLink$$uhttps://univsouthin.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-23497-7$$zOnline Access$$91397441.1 000737586 909CO $$ooai:library.usi.edu:737586$$pGLOBAL_SET 000737586 980__ $$aEBOOK 000737586 980__ $$aBIB 000737586 982__ $$aEbook 000737586 983__ $$aOnline 000737586 994__ $$a92$$bISE